Results 231 to 240 of about 3,960,591 (302)

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Transferability of Real World Evidence to Support HTA Recommendations in Lower Income European Countries. [PDF]

Health Sci Rep
Kaló Z, Petrova G, Németh B, Bonča PD, Delnoij D, Bennett A, Tachkov K, Zhang Y, Kreif N, Knies S, Lipska I, Tesar T, Mitkova Z, Ponten J, Viberg A, Paveliu MS, Piniazkho O, Turcu-Stiolica A, Doležal T, Staňák M, Almadiyeva A, Hren R, Vitezić D, Petykó Z, Goettsch W, Manca A.   +25 more
europepmc   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Antidiabetic Drug Associations With Heart Failure Outcomes: Real-World Evidence Study Using Electronic Health Records. [PDF]

JMIR Diabetes
Jodlowska-Siewert E, Chen Y, Zhang S, Li J, Dellavalle R, Zhang R, Hou J.   +6 more
europepmc   +1 more source

Editorial: Real-world data and real-world evidence in lung cancer

Frontiers in Oncology
Valerio Gristina, Chukwuka Eze
openaire   +3 more sources

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

O1 Impact of intravenous belimumab treatment on steroid use and disease activity in patients with Systemic Lupus Erythematosus (SLE) in the US in clinical practice: 24-month results from the OBSErve study

Lupus Science and Medicine
Robert Wood, Roger A Levy, Rosie Wild, Elke Rottier, Holly A Quasny, Marguerite Bracher, Seth Anderson, Daniel Moldaver, Alexandra Cusmano   +8 more
doaj   +1 more source

Optimizing Crohn's Disease Management in the Biologic Era-Insights from Real-World Evidence in Japan. [PDF]

JMA J
Fukuzawa M.
europepmc   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

Utilization of real-world evidence in regulatory approvals for multiple myeloma therapies. [PDF]

Blood Cancer J
Taylor L, Chen A, Pierre A.
europepmc   +1 more source