Results 261 to 270 of about 16,717,089 (314)

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Real-World Evidence of the Effectiveness and Safety of Biosynthetic Semaglutide in Type 2 Diabetes: A Multicentre Study From Pakistan. [PDF]

Diabetes Obes Metab
Hussain A, Wahab MU, Qureshi S, Raja UY, Munir A, Gardezi S, Iqbal M, Afzal B, Butt MD, Ong SC.   +9 more
europepmc   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Efficacy and safety of Omadacycline in community-acquired pneumonia among elderly patients: a real-world evidence study. [PDF]

Front Cell Infect Microbiol
Xie X, Deng J, Sun G, Song Y.
europepmc   +1 more source

Comment on 'Real-World Evidence of the Effectiveness and Safety of Biosynthetic Semaglutide in Type 2 Diabetes: A Multicentre Study From Pakistan'. [PDF]

Diabetes Obes Metab
Shahid F, Khan MF.
europepmc   +1 more source

Mapping TriNetX-Based Real-World Evidence Publications by Clinical Domain and Study Purpose, 2018-2025: A Bibliometric Analysis. [PDF]

Healthcare (Basel)
Hsieh MC, Lu MC, Koo M.
europepmc   +1 more source

Real-world evidence of sacituzumab govitecan in metastatic triple-negative breast cancer: an updated multicenter analysis. [PDF]

ESMO Open
Caputo R, Buono G, Martinelli C, Botticelli A, Caltavituro A, Pantano F, Guarino A, Bonomo MV, Diana A, Carlino F, Rizzo A, Giotta F, Orlando L, Sanò MV, Staropoli N, Von Arx C, Pernice G, Stucci S, Bajardi EA, Ricciardi GR, Turano S, Poggio FB, Cinieri S, Orditura M, Arpino G, Giuliano M, Fabi A, Piezzo M, Del Mastro L, De Laurentiis M.   +29 more
europepmc   +1 more source

Real-World Evidence of Upadacitinib Effectiveness in Moderate to Severe Atopic Dermatitis Patients in Saudi Arabia: A Retrospective Chart Review. [PDF]

Dermatol Res Pract
Saaty SEL, Alshehri HS, Alsharif O, Alali A, Fatani MI, Alajlan A, Hammad S, Elnahal I, Hamad T, Anwar A, Ahmed K.   +10 more
europepmc   +1 more source