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Real-world Evidence Simplified for Clinicians

Journal of The Association of Physicians of India
Real-world evidence (RWE) is rapidly becoming a crucial component in healthcare decision-making, complementing traditional clinical trial data. Randomized controlled trials (RCTs) are widely regarded as the most reliable method for assessing the efficacy and safety of medical treatments. RWE can enhance and support the results obtained from traditional
Abhijit Anil, Trailokya   +5 more
openaire   +2 more sources

Real-world evidence of allergen immunotherapy

Current Opinion in Allergy & Clinical Immunology
Purpose of review The full understanding of the long-term effectiveness and safety of allergen immunotherapy (AIT) for allergic respiratory diseases cannot be achieved through randomized controlled trials (RCTs) alone.
Buta, Federica   +5 more
openaire   +2 more sources

Raising the Impact of Real World Evidence

2019
In an environment in which most regulatory and authoritative health strategy decisions are made on the basis of randomised control trials, real-world evidence (RWE), primarily derived from electronic health records, remains a second-class citizen. Real world evidence is widely taken to include Pragmatic clinical trials and insights derived from the ...
openaire   +2 more sources

Using real-world evidence in haematology

Best Practice & Research Clinical Haematology
Most new drug approvals are based on data from large randomized clinical trials (RCTs). However, there are sometimes contradictory conclusions from seemingly similar trials and generalizability of conclusions from these trials is limited. These considerations explain, in part, the gap between conclusions from data of RCTs and those from registries ...
Passamonti, Francesco   +6 more
openaire   +2 more sources

Real-World Evidence - What Is It and What Can It Tell Us?

New England Journal of Medicine, 2016
Rachel E. Sherman   +14 more
semanticscholar   +1 more source

Biases in Electronic Health Records Data for Generating Real-World Evidence: An Overview

Journal of Healthcare Informatics Research, 2023
Ban Al-Sahab   +4 more
semanticscholar   +1 more source

An overview of real‐world data sources for oncology and considerations for research

Ca-A Cancer Journal for Clinicians, 2022
Jennifer L Lund   +2 more
exaly  

[All evidence is real world evidence.]

Recenti progressi in medicina, 2020
Randomized controlled trials are criticized for the difficulty of translating the results obtained to healthcare and clinical practice. The populations of patients enrolled in the studies are supposed to be too different from the patients encountered daily by the health professionals.
openaire   +1 more source

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