Results 51 to 60 of about 1,473,125 (294)

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

THE PERSPECTIVES OF EURO INTEGRATION IN ROMANIA, IN THE UNCERTAINTY CONTEXT AROUND THE FOREIGN MARKETS [PDF]

open access: yesAnnals of the University of Oradea: Economic Science, 2010
This paper has the object to analyze to what extent Romania fulfils the Maastricht criteria in comparison to some countries which are candidate members from Central Europe, in the todays unfavorable context which has been achieved under the actual global
Ciobanu (Sireteanu) Elena
doaj  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Euro Adoption in Romania: An Exploration of Convergence Criteria [PDF]

open access: yesOvidius University Annals: Economic Sciences Series, 2020
The aim of this paper is to analyze the position of Romania towards the Maastricht criteria, starting from the assumption that meeting the nominal convergence criteria is no longer enough for the Romanian adoption of euro. The most significant risks that
Georgiana-Loredana Schipor
doaj  

Subsequences of Real Valued Sequences and Convergence

open access: yesPeriodicals of Engineering and Natural Sciences (PEN), 2021
Convergence of real valued sequences is a classical subject of study for many mathematicians and it continues to be studied in recent years. Different types of convergence including ordinary, statistical, almost and ideal convergence, and related properties have been researched.
openaire   +1 more source

Molecular cancer prevention: Intercepting disease

open access: yesMolecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco   +2 more
wiley   +1 more source

Real Convergence in the Euro Area. Are the New Member States Catching Up or Falling Behind? [PDF]

open access: yesOvidius University Annals: Economic Sciences Series, 2020
The establishment of the Economic and Monetary Union and the accession of the Central and Eastern European countries have created both opportunities and challenges for the regional group.
Ana-Maria Holobiuc
doaj  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

THE COSTS AND BENEFITS OF ROMANIA'S ADERATION TO THE EURO ZONE AND ADOPTION OF THE UNIQUE CURRENCY [PDF]

open access: yesAnnals of the University of Oradea: Economic Science, 2010
The accession to the Economic and Monetary Union, though not a criterion of accessing the European Union, involves the compliance with the convergence criteria of Maastricht: stability of the exchange rate, of interest rates, of the inflation, of the ...
Hlaciuc Ana Maria   +1 more
doaj  

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