Results 111 to 120 of about 2,274,708 (332)

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

open access: yesMolecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi   +5 more
wiley   +1 more source

A small footprint couch‐top support device for image‐guided radiotherapy of heavy patients

open access: yesJournal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Purpose Patients with body weights close to or above 400 lbs present unique challenges in radiation therapy since the weight limit of most treatment couches decreases as the couch‐top extends toward the treatment gantry. The purpose of this work was to develop a small footprint couch‐top support platform to safely perform image‐guided ...
Huixiao Chen   +5 more
wiley   +1 more source

Building Bridges: Treating a New Transport Link as a Real Option [PDF]

open access: yes
A transportation investment that materially improves links between centres opens up previously unavailable options for new activities. Traditional cost-benefit analysis does not adequately take account of the value of this option; real options theory ...
Arthur Grimes
core   +3 more sources

ESG-Driven Investment Decisions in Photovoltaic Projects

open access: yesEnergies
As global climate change intensifies and environmental awareness increases, investing in renewable energy has become a primary economic and social development priority.
Ruolan Wei   +3 more
doaj   +1 more source

Real Options and Human Capital Investment [PDF]

open access: yes
This paper extends the standard human capital model with real options. Real options influence investment behavior when risky investments in human capital are irreversible and individuals can affect the timing of the investment.
Bas Jacobs
core  

Peripheral blood leukocyte signatures as biomarkers in relapsed ovarian cancer patients receiving combined anti‐CD73/anti‐PD‐L1 immunotherapy in arm A of the NSGO‐OV‐UMB1/ENGOT‐OV30 trial

open access: yesMolecular Oncology, EarlyView.
Using mass cytometry, we analyzed serial blood samples from patients with relapsed epithelial ovarian cancer (EOC) treated with oleclumab–durvalumab combination immunotherapy in the NSGO‐OV‐UMB1/ENGOT‐OV30 trial. Our analysis identified potential predictive, monitoring, and response biomarkers detectable through liquid biopsy. These findings facilitate
Luka Tandaric   +11 more
wiley   +1 more source

The application of multiple metrics in deformable image registration for target volume delineation of breast tumor bed

open access: yesJournal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Background and purpose For postoperative breast cancer patients, deformable image registration (DIR) is challenged due to the large deformations and non‐correspondence caused by tumor resection and clip insertion. To deal with it, three metrics (fiducial‐, region‐, and intensity‐based) were jointly used in DIR algorithm for improved accuracy ...
Xin Xie   +6 more
wiley   +1 more source

Neural Network Learning of Black-Scholes Equation for Option Pricing [PDF]

open access: yesarXiv
One of the most discussed problems in the financial world is stock option pricing. The Black-Scholes Equation is a Parabolic Partial Differential Equation which provides an option pricing model. The present work proposes an approach based on Neural Networks to solve the Black-Scholes Equations. Real-world data from the stock options market were used as
arxiv  

Valuation of a Company Producing and Trading Seaweed for Human Consumption: Classical Methods vs. Real Options. [PDF]

open access: yesInt J Environ Res Public Health, 2021
Pérez-Vas R   +2 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy