Results 131 to 140 of about 3,743,885 (328)

Trifluridine/tipiracil as a therapeutic option in real life setting of metastatic colorectal cancer: An efficacy and safety analysis [PDF]

open access: gold, 2022
Daniel Sur   +6 more
openalex   +1 more source

A Reply to “Option Value of Harvesting†Revisited (The Comment) [PDF]

open access: yes
Li’s results (1998) are correct and robust. The Comment offers an interesting perspective from real-options theory, albeit misguided--from a resource-economics point of view.
Li, Eric A.L.
core   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

USING REAL OPTIONS TO EVALUATE PRODUCER INVESTMENT IN NEW GENERATION COOPERATIVES [PDF]

open access: yes
New Generation Cooperatives have emerged as a contemporary means for farmers to invest in further processing activities. This paper considers real options as the basis for evaluating producer investment in a start-up cooperative that involves ...
Bailey, Michael D., Sporleder, Thomas L.
core   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

Real Options: Applications in Public Economics [PDF]

open access: yes
This paper illustrates the use of real options principles to value prototypical resource and industryinvestment projects. It captures important competitive/strategic dimensions in a step-by-stepanalysis of investment decisions (options) under uncertainty.
Lawrence, Craig, Thomas, Mathew
core   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Investment in Wind Power and Pumped Storage in a Real Options Model - A Policy Analysis [PDF]

open access: bronze, 2011
Wolf-Heinrich Reuter   +3 more
openalex   +1 more source

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