Results 71 to 80 of about 613,391 (263)

Use coal or invest in renewables: a real options analysis of energy investments in the Philippines

Renewables: Wind, Water, and Solar, 2018
This paper aims to analyze the comparative attractiveness of either investing in various renewable energy sources or continue using coal for electricity generation in the Philippines.
Casper Boongaling Agaton
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

OPPORTUNITIES AND LIMITATIONS OF USING THE METHOD OF REAL OPTIONS IN EVALUATION OF INNOVATION PROJECTS

Вестник Северо-Кавказского федерального университета, 2022
The purpose of this study is to investigate the possibilities and limitations of using the real option method when evaluating innovative projects. To achieve this goal, an analysis of the theoretical, analytical, empirical and methodological support for ...
Elena Makarova, Maria Novoselova
doaj  

Subsidy policy selection of elderly care service projects under uncertain actual demand: a real options analysis based on China's experience. [PDF]

BMC Geriatr, 2022
Song H, Ji K, Sun T.
europepmc   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

A comprehensive analysis of real options in solar photovoltaic projects: A cluster-based approach

Heliyon
Solar photovoltaic (PV) projects are pivotal in addressing climate change and fostering a sustainable energy future. However, the complex landscape of renewable energy investments, characterized by high upfront costs, market uncertainties, and evolving ...
L.M. Jiménez-Gómez, J.D. Velásquez-Henao   +1 more
doaj   +1 more source

A volatilidade de projetos industriais para uso em análise de risco de investimentos The volatility of industrial projects for use in analysis of risk in investments

Gestão & Produção, 2012
A volatilidade em projetos industriais é um parâmetro significativo na análise de risco de investimentos. Quando se avaliam ativos financeiros, a volatilidade pode ser determinada por meio de dados históricos do ativo, porém, ao se trabalhar com projetos
Ronildo Jorge de Oliveira, Edson de Oliveira Pamplona   +1 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source