Results 91 to 100 of about 9,000,641 (233)
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Real sequence effects on the search dynamics of transcription factors on DNA. [PDF]
Sci Rep, 2015 Bauer M +3 more
europepmc +1 more source
Sign.: []1, A-P8Texto con apostillas marginalesPortada con escudo real ...
Real Acequia de Jarama
core
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Sequence-Activated Fluorescent Nanotheranostics for Real-Time Profiling Pancreatic Cancer
JACS Au, 2022 Yining Tao +7 more
doaj +1 more source
Corrigendum: Real sequence effects on the search dynamics of transcription factors on DNA. [PDF]
Sci Rep, 2015 Bauer M +3 more
europepmc +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
On paranormed type fuzzy I -convergent double multiplier sequences
Kuwait Journal of Science, 2013 In this article, we introduce the classes of fuzzy real valued double sequences and , where is a multiplier sequence of non-zero real numbers and is a double sequence of bounded strictly positive numbers.
M. SEN, S. ROY
doaj