Results 81 to 90 of about 72,553 (251)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Sequence Evaluation in Real Time

open access: yes, 2023
The ability to identify and characterize the function of an unknown pathogen, such as a virus, bacteria, or toxin, from its biological sequence is critical to quickly determine the potential impact against human health.

core  

Parameterization of Perfect Sequences of Real Numbers

open access: yesIEICE Transactions on Fundamentals of Electronics, Communications and Computer Sciences, 2011
A perfect sequence is a sequence having an impulsive autocorrelation function. Perfect sequences have several applications, such as CDMA, ultrasonic imaging, and position control. A parameterization of a perfect sequence is presented in the present paper. We treat a set of perfect sequences as a zero set of quadratic equations and prove a decomposition
Takao Maeda, Takafumi Hayashi
openaire   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

GASP: gapped ancestral sequence prediction for proteins

open access: yes, 2004
Background: the prediction of ancestral protein sequences from multiple sequence alignments is useful for many bioinformatics analyses. Predicting ancestral sequences is not a simple procedure and relies on accurate alignments and phylogenies.
Denis C. Shields (18564)   +7 more
core   +1 more source

Sample of blink sequence pattern for real and fake video.

open access: yes, 2022
Sample of blink sequence pattern for real and fake video.
Norasyikin Fadilah (14266029)   +4 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

A new study on the strongly lacunary quasi Cauchy sequences

open access: yesSakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 2018
In this paper, the concept ofan -quasi-Cauchysequence is introduced. We proved interesting theorems related to -quasi-Cauchysequences. A real valued function defined on a subset of , the set of real numbers, is -ward continuous on if it preserves -quasi ...
Huseyin Cakalli, Hüseyin Kaplan
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Configurable and Up-Scalable Microfluidic Life Science Platform for Cell Based Assays by Gravity Driven Sequential Perfusion and Diffusion

open access: yes, 2010
Microfluidics has the potential to significantly change the way modern biology is performed, but for this potential to be realized several on-chip integration and operation challenges have to be addressed.
Dimov, Ivan Krastev
core  

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