Results 141 to 150 of about 13,182,333 (255)

A Typology of Approaches for Real-time Monitoring

In recent years, the World Bank’s Poverty and Equity Global Practice (GP) has increased its capacity to provide more timely information on welfare.
World Bank
core   +1 more source

Adherence to Biologic Therapies is Associated with Improved Clinical Outcomes and Reduced Healthcare Resource Utilization in Patients with Severe Asthma in Japan

Journal of Asthma and Allergy
Hiroyuki Nagase,1 Urvee Karsanji,2 Hideaki Kunishige,3 Takeo Suzuki,4 Anna Vichiendilokkul,5 Liza Yuanita,6 Natsuki Sasakura,6 Jiaxuan Wang,7 Saeed Noibi8 1Division of Respiratory Medicine and Allergology, Department of Medicine, Teikyo University School
Nagase H, Karsanji U, Kunishige H, Suzuki T, Vichiendilokkul A, Yuanita L, Sasakura N, Wang J, Noibi S   +8 more
doaj  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Is AI Capable of Real-World Drug Discovery? [PDF]

J Chem Inf Model
McGaughey G.
europepmc   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Pathways to Real World Evidence From the Real World of School-Based Physical Fitness Testing (SB-PFT). [PDF]

Learn Health Syst
Walden A, Yiu A, Welk G, Guo Y, Radom-Aizik S, Schneider M, Reeds A, Shakir A, Cooper DM.   +8 more
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Confusing Uncertainty With Bias: The Challenges of Working With Real-World Data. [PDF]

Drug Alcohol Rev
Wilson J, Sunderland M, O'Dean S, Slade T, Dawson D, Dobson O, Leung J, Chan G, Teesson M, Hall W, Newton N, Lorenzetti V, Stockings E.   +12 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Renal Denervation: A Multicenter, Real-World Experience. [PDF]

Cardiol Res
Rao S, Rao KR, Pillai A, Patil A, Kapadiya A, Gopi A, Swaroop G, Ingle H, Parikh K, Mahesh NK, Shah N, Chandra P, Singh RP, Natarajan R, Rao RS, Showkathali R, Sharma SM, Sathe S, Banerjee S, Rajasekhar V, Rao VSP, Kumar V, Reddy YV.   +22 more
europepmc   +1 more source