Results 161 to 170 of about 188,752 (308)

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

Development and preliminary validation of a hybrid three-dimension printed model for glaucoma drainage device surgery training: a prospective simulation-based study. [PDF]

BMC Ophthalmol
Al Owaifeer AM, Al-Yahya A, Allubly AM, Alalmaee KA, Alqurashi A, AlKaff A, AlShahwan S.   +6 more
europepmc   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Design, Implementation, and Effectiveness of Virtual Reality and Digital Simulation Tools for Pediatric Dental Behavior Management Education: Systematic Review. [PDF]

JMIR Serious Games
Shi Q, Lyu L, He J, Jiang W, Pang M, Chen J, Wu Z.   +6 more
europepmc   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Ontic Structural Realism, Information, and Natural Necessity: Where Naturalism and Analytic Metaphysics Can Find Common Ground [PDF]

J. Ladyman (1998-2009), Ladyman and Ross (2007) refine J. Worral's (1998) structural realism (SR), by developing an ontic structural realism (OSR) which they argue is a consistently naturalistic means of characterizing the ontology of fundamental physics.
Kallfelz, William
core  

A Reproducible Digital Workflow for Patient-Specific 3D-Printed Teeth with Anatomically Stratified Enamel and Multi-Material Caries for Preclinical Operative Dentistry. [PDF]

J Funct Biomater
Micu AM, Bacalu RM, Constantin TR, Cârstea AE, Ciocan LT, Vasilescu VG, Dimitriu B, Pantea M, Pițuru SM, Imre M.   +9 more
europepmc   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Kant's Transcendental Idealism and Contemporary Anti-Realism

, 2003
This paper compares Kant's transcendental idealism with three main groups of contemporary anti-realism, associated with Wittgenstein, Putnam, and Dummett, respectively.
Lucy Allais (16059272)
core  

Considering the ethics of live tissue training in trauma surgery. [PDF]

J Med Ethics
Swain C, Rickard R, Karlgren K, Helgesson G.   +3 more
europepmc   +1 more source