Results 71 to 80 of about 128,797 (311)
Rationalist and Sentimentalist Realism: A Re-examination of the Types of Metaethical Realism and Their Implications [PDF]
SUBJECT & OBJECTIVES: Ontological inquiry constitutes one of the central concerns of metaethics. Within this field, theories are commonly divided into two main categories: realist and non-realist.
Ali Ahmadi Amin, Mohammad Mahdi Monadi
doaj +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Scientific Realism, the Galilean Strategy, and Representation [PDF]
This paper critically reviews Philip Kitcher’s most recent epistemology of science, real realism. I argue that this view is unstable under different understandings of the term “representation”, and that the arguments offered for the position are either ...
Suárez, Mauricio
core
Liquid Realism: Hauntology, Lack, and Mourning as Method
This article proposes liquid realism as a term to describe a critical stance that constitutes a metamodern methodology. Drawing on Zygmunt Bauman’s liquid modernity, Mark Fisher’s hauntology, and Jacques Lacan’s conception of the real as structural lack,
Edgar Robert
doaj +1 more source
Realism is an approach and paradigm that is in international relations, Realism began to be debated during World War II (World War II) because of the failure of the League of Nations (LBB).
Taufan Herdansyah Akbar +2 more
doaj +1 more source
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Political realism, Freud, and human nature in international relations [PDF]
Political realism has enjoyed a renaissance in International Relations (IR). Recent studies have provided insightful accounts of its timeless virtues and philosophical depth.
Schütt, Robert, Schuett, R
core
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Experimental Realism Defended: How Inference to the Most Likely Cause Might Be Sound [PDF]
On a purely epistemic understanding of experimental realism, manipulation affords a particularly robust kind of causal warrant, which is – like any other warrant – defeasible.
Suárez, Mauricio, Mauricio Suárez
core

