Results 91 to 100 of about 568,913 (306)
Nonconceptual Content, Causal Theory, and Realism
The Baltic International Yearbook of Cognition, Logic and Communication, 2014 In this paper the connections between the nonconceptual content of perceptual states and realism are considered. In particular, I investigate the argument for realism that uses the notion of nonconceptual content, specifically the version proposed by ...
Błażej Skrzypulec
doaj +1 more source
International Legal Positivism and Legal Realism [PDF]
, 2013 This chapter, a contribution to a book on International Legal Positivism in a Post-Modern World, gauges the potential for mutually enriching interactions between international legal positivism and legal realism.
Telman, D. A. Jeremy
core +2 more sources
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Moral Realism and Anti-Realism in Later Wittgenstein
Metaphysics, 2011 By emphasis on cognitive aspect of moral realism, this article surveys various divisions in moral realism and anti-realism and, regarding later Wittgenstein's courses, it explores his views about this matter.
A Sabramiz, S Dabagh
doaj
The Significance of Being Ethical: An essay on the case for moral realism and theism
Scientia et Fides, 2016 William Irwin defends a form of moral anti-realism, according to which there are no objective moral facts. He contends that moral realism is objectionable because of its being more complex or not as simple as anti-realism; moral realism is in conflict ...
Charles Taliaferro
doaj +1 more source
Color Realism: True or Not? [PDF]
, 2017 Color realism refers to that things are colored, or colors are real. Although the view goes in a minority opinion, Byrne & Hilbert defend it based on the physical properties of color and the peculiarly assumed hue-magnitudes.
ma, Z. G.
core +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Internal Realism and the Reality of God [PDF]
, 2014 How do religions refer to reality in their language and symbols, and which reality do they envisage and encounter? on the basis of some examples of an understanding of religion without reference to reality, I first answer the question of what ”realism ...
Grosshans, Hans-Peter
core +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source