Results 81 to 90 of about 128,797 (311)
Empirical realism and the legitimacy of ontology: A dialogue [PDF]
, 2015 The purpose of this dialogue between an ‘empirical realist’ and a ‘traditional ontologist’ is to clarify and evaluate the presuppositions of the kind of antiontological position exemplified by empirical realism.
McWherter, Dustin
core +1 more source
Moral Realism and Anti-Realism in Later Wittgenstein
Metaphysics, 2011 By emphasis on cognitive aspect of moral realism, this article surveys various divisions in moral realism and anti-realism and, regarding later Wittgenstein's courses, it explores his views about this matter.
A Sabramiz, S Dabagh
doaj
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Assessing the visual realism of deepfake videos: an IQA-based approach [PDF]
PeerJ Computer ScienceAs deepfake videos become increasingly realistic, the ability of detection models to generalize across manipulation techniques with varying degrees of visual realism has become critical.
Ahmet Demir +2 more
doaj +2 more sources
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Why the Ultimate Argument for Scientific Realism Ultimately Fails [PDF]
, 2011 In this paper, I argue that the ultimate argument for Scientific Realism, also known as the No-Miracles Argument (NMA), ultimately fails as an abductive defence of Epistemic Scientific Realism (ESR), where (ESR) is the thesis that successful theories of ...
Mizrahi, Moti
core
Nonconceptual Content, Causal Theory, and Realism
The Baltic International Yearbook of Cognition, Logic and Communication, 2014 In this paper the connections between the nonconceptual content of perceptual states and realism are considered. In particular, I investigate the argument for realism that uses the notion of nonconceptual content, specifically the version proposed by ...
Błażej Skrzypulec
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source