Results 111 to 120 of about 128,797 (311)

ROMAN INGARDEN: OD REALIZMU FENOMENOLOGICZNEGO DO MORALNEGO [PDF]

open access: yesThe Polish Journal of Aesthetics, 2003
Man is the cornerstone of Ingarden's philosophy. His position in his essay “On Responsibility” marks confirmation of his permanent interest in man and the final departure from the idealism-realism problematic.
Edward M. Swiderski
doaj  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Thinking About the Ultimate Argument for Realism [PDF]

open access: yes, 2003
The aim of this paper is to rebut two major criticisms of the No-Miracles Argument for Realism. The first comes from Musgrave (1988). The second comes from Colin Howson (2000).
Psillos, Stathis
core  

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Can van Fraassen's anti-realism give an account of novel predictions of unexpected phenomena? [PDF]

open access: yes, 2011
In this paper it will be addressed the possibility of an account of novel predictions of unexpected phenomena by physical theories within van Fraassen's anti-realism.
Bacelar Valente, Mario
core  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Algumas notas sobre “realismo” e “ultrarealismo” em Sartre

open access: yesDoisPontos, 2006
This paper intends to research the possibility of thinking the several elements of Sartre's works according to one axe named "realism". It is important to explain what "realism" means here. Not intending find out a definition of "realism". Here "realism"
Alexandre de Oliveira Torres Carrasco
doaj  

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

"Critical Realism and the Political Economy of the Euro" [PDF]

open access: yes
This paper is concerned with two issues. First, it discusses some of the main problems and inferences the methodological approach of critical realism raises for empirical work in economics, while considering an approach adopted to try to overcome these ...
Malcolm Sawyer   +2 more
core  

Critical Realism, Gender and Feminism : Exchanges, Challenges, Synergies

open access: yes, 2016
Editorial to the special issue of JCR on Critical Realism, Gender and ...
Gunnarsson, Lena,   +2 more
core   +1 more source

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