Results 131 to 140 of about 188,752 (308)
Can van Fraassen's anti-realism give an account of novel predictions of unexpected phenomena? [PDF]
, 2011 In this paper it will be addressed the possibility of an account of novel predictions of unexpected phenomena by physical theories within van Fraassen's anti-realism.
Bacelar Valente, Mario
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Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Thinking About the Ultimate Argument for Realism [PDF]
, 2003 The aim of this paper is to rebut two major criticisms of the No-Miracles Argument for Realism. The first comes from Musgrave (1988). The second comes from Colin Howson (2000).
Psillos, Stathis
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Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
"Critical Realism and the Political Economy of the Euro" [PDF]
This paper is concerned with two issues. First, it discusses some of the main problems and inferences the methodological approach of critical realism raises for empirical work in economics, while considering an approach adopted to try to overcome these ...
Malcolm Sawyer +2 more
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Realistic Aspects in the Standard Interpretation of Quantum Mechanics
Humana.Mente: Journal of Philosophical Studies, 2018 The belief that quantum mechanics (QM) does not admit a realistic interpretation is widespread. According to some scholars concerned with the foundations of QM all existing interpretations of this theory (except for the statistical interpretation ...
Claudia Garola, Sandro Sozzo
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Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
, 2005 This paper first revisits the discussion between Tony Lawson and Sandra Harding in the journal Feminist Economics in light of the author’s own research into basic mechanisms of capitalist economies, research that has been influenced by feminist ...
Brown, G. +2 more
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Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source