Results 81 to 90 of about 4,584,624 (305)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

A Cascade Ensemble Learning Model for Human Activity Recognition with Smartphones

open access: yesSensors, 2019
Human activity recognition (HAR) has gained lots of attention in recent years due to its high demand in different domains. In this paper, a novel HAR system based on a cascade ensemble learning (CELearning) model is proposed.
Shoujiang Xu   +3 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Complex Reflectivity Modulation Characteristics at Visible Wavelength Using Liquid Crystal on a Metasurface Device

open access: yesAdvanced Photonics Research
Active metasurface device capable of complex modulation in the visible light range is demonstrated. To realize complex modulation, a liquid crystal (LC) of twisted nematic mode on a plasmonic antenna metasurface, where resonance wavelength is sensitive ...
Yong‐Hae Kim   +8 more
doaj   +1 more source

Modeling reality [PDF]

open access: yes
Although powerful computers have allowed complex physical and manmade hardware systems to be modeled successfully, we have encountered persistent problems with the reliability of computer models for systems involving human learning, human action, and ...
Denning, Peter J.
core   +1 more source

Chasing Success: A Cultivated Reality [PDF]

open access: yes, 2018
George Gerbner’s cultivation theory claims that people who consume heavy amounts of media are more likely to be influenced by those messages to believe the media reality as opposed to actual reality.
Bevillard, Anastasia
core   +1 more source

The concept of strong and weak virtual reality

open access: yes, 2006
We approach the virtual reality phenomenon by studying its relationship to set theory, and we investigate the case where this is done using the wellfoundedness property of sets.
A. Baltag   +7 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Comprehensive Health Insurance: The Reality [PDF]

open access: yes, 1972
In his article, Dr. O\u27Keefle outlines the major proposals (both generic and specIfic) in the area of national health insurance. He then describes in depth the proposed Warren County Plan and the Foundation Concept in relation to three fundamental ...
O\u27Keeffe, Daniel
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

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