Results 81 to 90 of about 1,759,701 (310)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Active electronic skin: an interface towards ambient haptic feedback on physical surfaces

open access: yesnpj Flexible Electronics
In the era of ubiquitous computing with flourished visual displays in our surroundings, the application of haptic feedback technology still remains in its infancy.
Yuan Guo   +6 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Exploration of OLED structures for high-resolution microdisplays with enhanced efficiency and color gamut

open access: yesJournal of Information Display
The subpixel size of high-resolution organic light-emitting diode (OLED) microdisplays measures a few micrometers. To achieve a full-color microdisplay, the current preference is to use photolithography technology on a white OLED instead of using a fine ...
Hyunsu Cho   +8 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Enhancing First-Person View Task Instruction Videos with Augmented Reality Cues

open access: yes, 2020
This research investigates enhancing first-person view (FPV) task instruction videos by applying Augmented Reality (AR) visualisation of spatial cues.
William Hoff   +7 more
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Mobile cross reality for cultural heritage [PDF]

open access: yes, 2013
Widespread adoption of smartphones and tablets has enabled people to multiplex their physical reality, where they engage in face-to-face social interaction, with Web-based social networks and apps, whilst emerging 3D Web technologies hold promise for ...
Miller, Alan Henry David   +6 more
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

A Cascade Ensemble Learning Model for Human Activity Recognition with Smartphones

open access: yesSensors, 2019
Human activity recognition (HAR) has gained lots of attention in recent years due to its high demand in different domains. In this paper, a novel HAR system based on a cascade ensemble learning (CELearning) model is proposed.
Shoujiang Xu   +3 more
doaj   +1 more source

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