Results 41 to 50 of about 117,304 (262)

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Comparing the efficacy of reality therapy with acceptance and commitment therapy on feelings of loneliness of adolescents [PDF]

مجله علوم روانشناختی
Background: Adolescents are in special and critical situations and sometimes they may distance themselves from society due to hormonal and appearance changes. This avoidance can create feelings of loneliness and isolation. Research on teenagers is one of
Ehsan Abron, Leila Sadat Azizi, Afsaneh Khajevand Khosheli   +2 more
doaj  

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

The efficacy of reality therapy education on self-efficacy and spouse selection criteria in single students [PDF]

مجله علوم روانشناختی
Background: Belief in intrinsic capabilities refers to valuing a specific set of cognitive strengths. Numerous studies have indicated significant relationships between self-efficacy and spouse selection criteria.
Shideh Fasahati, Ali Shirafkan Kopken, Mohammad Ghamari   +2 more
doaj  

The efficacy of reality therapy on differentiation and distress tolerance of mothers of intellectual disabilitie children

مجله علوم روانشناختی, 2022
Background: Studies suggest the positive effects of reality therapy on mood and emotional disorders. It teaches people to be aware of their basic needs and emphasizes coping with reality, responsibility, and evaluation of right and wrong behaviors ...
Maryam Tofighi Mohammadi, Vahideh Babakhani, Mohammad Ghamari, Jafar Pooyamanesh   +3 more
doaj  

The effectiveness of choice theory training on the mental health of adolescent girls

International Archives of Health Sciences, 2020
Purposes: The purpose of the present study was to investigate the effectiveness of choice theory on the mental health of students. Materials and Methods: The present study followed a quasi-experimental method with pretest-posttest design with a control ...
Fatemeh Zare, Fahimeh Namdarpour
doaj   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Comparison of the Effect of Group Couple Therapy Based on Reality Therapy and Acceptance and Commitment Therapy on Perfectionism and Adjustment of Couples\' Needs

تحقیقات نظام سلامت, 2021
Background: Perfectionism is a personality trait whose negative aspect becomes obsessive and causes many problems for the individual and the family.
Narges Afghari, Fariba Yazdkhasti, Hoseinali Mehrabi-Koushki, Akram Azimi   +3 more
doaj  

Comparison of the effectiveness of reality therapy and logotherapy on the components on forgiveness and marital trust of women affected by marital infidelity seeking divorce [PDF]

مجله علوم روانشناختی, 2023
Background: Systematic review of research shows that infidelity and marital infidelity cause the most damage to the relationship between spouses and can even destroy the relationship.
maryam Gholipour Firozjaei, Farideh Dokaneifard, Pantea Jahangir   +2 more
doaj