Results 41 to 50 of about 1,792 (273)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

The knowledge absorptive capacity to improve the cooperation and innovation in the firm

open access: yesJournal of Industrial Engineering and Management, 2018
Purpose: The purpose of this paper is to study the absorptive capacity types in the knowledge management literature and aims to understand how companies can strength their contexts of cooperation in order to innovate.
Lourdes Saiz   +2 more
doaj   +1 more source

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

open access: yesFEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber   +7 more
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Gatekeepers of Knowledge versus Platforms of Knowledge: From Potential to Realized Absorptive Capacity [PDF]

open access: yesRegional Studies, 2008
Abstract. The development of clusters rests through geographical proximity, cognitive interactions as well as entrepreneurial initiatives. Sophia-Antipolis, a multi-technology cluster, is a good illustration of the type of challenges local systems of innovation face in creating positive knowledge externalities. This paper shows that if the existence of
Longhi, Christian   +2 more
openaire   +3 more sources

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Combined Influence of Absorptive Capacity and Corporate Entrepreneurship on Performance [PDF]

open access: yes, 2019
Drawing on a dynamic capabilities perspective and a resource-based view, this article analyzes the relationship between absorptive capacity and corporate entrepreneurship, and their combined e ect on organizations’ performance.
García Morales, Víctor Jesús   +5 more
core   +1 more source

Unlocking the secrets of business intelligence and analytics in driving brand innovation: insights from an empirical study using SEM and fsQCA

open access: yesCogent Business & Management
While business intelligence and analytics (BI&A) hold significant potential for enterprise innovation, their role in driving brand innovation remains underexplored.
Zhe Xu, Xiang-Yun Xu
doaj   +1 more source

The impact of dynamic marketing capabilities on startup performance: A case of business incubators in Jordan [PDF]

open access: yesInnovative Marketing
Dynamic marketing capabilities provide startups with the platform and market knowledge that entitle them to achieve their goals and survive the competition.
Hamza Salim Khraim
doaj   +1 more source

Home - About - Disclaimer - Privacy