Results 31 to 40 of about 1,442 (237)

Transfer of knowledge in international cooperation: the Farmanguinhos – SMM case

Revista de Saúde Pública, 2017
OBJECTIVE To analyze the influence of four mechanisms of knowledge transfer (training, technical visits, expatriation, and standard operating procedures) on the different dimensions (potential and realized) of absorptive capacity in international ...
Samuel Araujo Gomes da Silva, Roberto Gonzalez Duarte, José Márcio de Castro   +2 more
doaj   +1 more source

Interorganizational learning and absorptive capacity: empirical research in small and medium enterprises / Aprendizagem interorganizacional e capacidade absortiva: investigação em pequenas e médias empresas

RAM. Revista de Administração Mackenzie, 2021
Purpose: This research analyzes the influence of interorganizational learning (IOL) on the absorptive (Acap), potential (Pacap) and realized (Racap) capacities on the environment of small and medium enterprises (SMEs).
Alessandra Cassol , Márcio L. Marietto , Graciele Tonial , Nathalia B. Werlang   +3 more
doaj   +1 more source

Absorptive Capacity, Business Venturing and Performance: Corporate Governance Mediating Roles

Cogent Business & Management, 2020
This study offers insight through Structural Equation Modeling (SEM) into the joint impact of corporate absorptive capacity and corporate new business venturing on the performance of manufacturing firms in Nigeria as moderated by the quality governance ...
Cosmas Ikechukwu Asogwa, Osmund Chinweoda Ugwu, Anthonia Uju Uzuagu, Samson Ige Abolarinwa, Godwin Keres Okoro Okereke, Honesta Chidiebere Anorue, Favour Amarachi Moghalu   +6 more
doaj   +1 more source

The knowledge absorptive capacity to improve the cooperation and innovation in the firm

Journal of Industrial Engineering and Management, 2018
Purpose: The purpose of this paper is to study the absorptive capacity types in the knowledge management literature and aims to understand how companies can strength their contexts of cooperation in order to innovate.
Lourdes Saiz, David Pérez Miguel, Miguel Ángel Manzanedo del Campo   +2 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Unlocking the secrets of business intelligence and analytics in driving brand innovation: insights from an empirical study using SEM and fsQCA

Cogent Business & Management
While business intelligence and analytics (BI&A) hold significant potential for enterprise innovation, their role in driving brand innovation remains underexplored.
Zhe Xu, Xiang-Yun Xu
doaj   +1 more source

Gatekeepers of Knowledge versus Platforms of Knowledge: From Potential to Realized Absorptive Capacity [PDF]

Regional Studies, 2008
Abstract. The development of clusters rests through geographical proximity, cognitive interactions as well as entrepreneurial initiatives. Sophia-Antipolis, a multi-technology cluster, is a good illustration of the type of challenges local systems of innovation face in creating positive knowledge externalities. This paper shows that if the existence of
Longhi, Christian, Thomas, Catherine, Lazaric, Nathalie   +2 more
openaire   +3 more sources