Results 71 to 80 of about 20,710 (283)

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

The Under-Developed Social Integration Mechanism as Moderating Factor of Two-Dimensional Absorptive Capacity Relationship: Systematic Literature Review

SAGE Open
The study aims to answer how and what kind of the social integration mechanisms may influence the relationship between the two dimensions of absorptive capacity which is, potential absorptive capacity (PACAP) and realized absorptive capacity (RACAP). The
Asri Pertiwi, Tirta Nugraha Mursitama, Jap Tji Beng, Elidjen   +3 more
doaj   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

The Implementation of Using Role playing Method to Improve Cognitive Aktivities and Learning Outcomes Students' on Excretion System Material in SMPN 1 Batang

Unnes Journal of Biology Education, 2018
One of the main learning problems in school today is the low absorptive capacity of students as evidenced by the average of the student’s learning outcomes is always still under KKM.
Daniar Arof Adiba, Sri Mulyani Endang Susilowati, Ari Yuniastuti   +2 more
doaj   +1 more source

The Multinational Corporation and the Global Sourcing of Knowledge: Remodeling Absorptive Capacity [PDF]

We build on extant theory of the MNC, MNC subsidiaries, absorptive capacity and Penrose's concept of 'productive opportunity' to develop a framework on the MNC and absorptive capacity (AC) that allows us to explore the role of subsidiaries in the global ...
Kottaridi, Constantina, Papanastassiou, Marina, Pitelis, Christos, Thomakos, Dimitrios   +3 more
core  

A Network Perspective on Inter-Organizational Transfer of R&D Capabilities: A Study of International Joint Ventures in Chinese Automobile Industry [PDF]

, 2001
Multinational enterprises' transfer of R&D capabilities to their international joint ventures in the less developed countries has been an emerging phenomenon.
Anand, Jaideep, Mitchell, Will, Zhao, Zheng   +2 more
core   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Remaining Innovative: The Role of Past Performance, Absorptive Capacity, and Internationalization

BBR: Brazilian Business Review, 2017
Emerging markets firms are tardy regarding innovativeness and international orientation. Despite that, some of these firms are becoming increasingly competitive regarding innovation and internationalization.
Ivan Lapuente Garrido, Ronaldo Couto Parente, Cláudio Reis Gonçalo, Sílvio Luís de Vasconcellos   +3 more
doaj  

Absorptive capacity of industrial companies in traditional sectors in the state of Rio Grande do Sul, Brazil / Uma análise da capacidade absortiva em empresas de setores tradicionais do Rio Grande do Sul

RAM. Revista de Administração Mackenzie, 2019
Purpose: This study aimed to assess processes related to absorptive capacity (AC) dimensions in innovation-generating companies of traditional sectors in the State of Rio Grande do Sul, Brazil.
Clair W. Puffal, Daniel P. Puffal , Yeda S. Souza   +2 more
doaj   +1 more source