Results 81 to 90 of about 32,209 (206)

MyD88 Deficiency Protects Mice From Experimental Autoimmune Encephalomyelitis by Influencing Both Dendritic Cells and T Cells

Immunology, Volume 177, Issue 4, Page 784-797, April 2026.
This study investigates the role of MyD88 in dendritic cells (DCs) and T cells during experimental autoimmune encephalomyelitis (EAE). We found that MyD88 is highly expressed in DCs and CD4+ T cells in people with multiple sclerosis, and its deficiency impairs DC maturation, reduces pro‐inflammatory cytokine production, weakens DC–T cell interactions ...
Wen Si, Gaochen Zhu, Qianling Jiang, Xin Ma, Guan Yang   +4 more
wiley   +1 more source

EZH2 upregulation by ERα induces proliferation and migration of papillary thyroid carcinoma

BMC Cancer, 2019
Background The incidence of papillary thyroid carcinoma (PTC) has been increasing worldwide in recent years. Therefore, novel potential therapeutic targets for PTC are urgently needed.
Liqiong Xue, Hongzhu Yan, Ying Chen, Qifa Zhang, Xin Xie, Xiaoying Ding, Xiaojing Wang, Zhongqing Qian, Feng Xiao, Zhiyi Song, Yijie Wu, Yongde Peng, Huanbai Xu   +12 more
doaj   +1 more source

Longitudinal Analysis of Antibody Responses to Trachoma Antigens Before and After Mass Drug Administration. [PDF]

, 2014
Blinding trachoma, caused by the bacteria Chlamydia trachomatis, is a neglected tropical disease targeted for elimination by 2020. A major component of the elimination strategy is mass drug administration (MDA) with azithromycin.
Dize, Laura, Gaydos, Charlotte, Goodhew, Erica Brook, Lammie, Patrick J, Martin, Diana L, Mkocha, Harran, Morgan, Sheri Maria, Munoz, Beatriz, Switzer, Andrew J, West, Sheila K, Wiegand, Ryan E   +10 more
core   +2 more sources

DNA Virus Detection in Olfactory Neuroblastomas Using Targeted Enrichment NGS

Neuropathology, Volume 46, Issue 2, April 2026.
ABSTRACT A variety of malignancies can be found in the sinonasal tract including the nasal cavity, paranasal sinuses, and skull base. Many of these are attributed to viruses, for example, carcinomas with the presence of transcriptionally active high‐risk human papillomavirus, as well as Epstein–Barr virus associated malignant lymphoepithelial carcinoma
Maria K. Jauhiainen, Outi I. Mielonen, Aaro Haapaniemi, Maria Söderlund‐Venermo, Jaana Hagström, Maria F. Perdomo, Saku T. Sinkkonen, Antti A. Mäkitie   +7 more
wiley   +1 more source

Real-time PCR for mRNA quantitation

BioTechniques, 2005
Real-time PCR has become one of the most widely used methods of gene quantitation because it has a large dynamic range, boasts tremendous sensitivity, can be highly sequence-specific, has little to no post-amplification processing, and is amenable to ...
Marisa L. Wong, Juan F. Medrano
doaj   +1 more source

Cytotoxic effects of Oosporein isolated from endophytic fungus Cochliobolus kusanoi

Frontiers in Microbiology, 2015
In the present study, oosporein, a fungal toxic secondary metabolite known to be a toxic agent causing chronic disorders in animals, was isolated from fungus Cochliobolus kusanoi of Nerium oleander L.
Rmaesha eA, VENKATARAMANA eM, Nirmaladevi eD, Vijai Kumar Gupta, Chandra eNayak, Srinivas eC   +5 more
doaj   +1 more source

Oncogenic microRNAs characterization in clear cell renal cell carcinoma [PDF]

, 2015
A key challenge for the improvement of clear cell renal cell carcinoma (ccRCC) management could derive from a deeper characterization of the biology of these neoplasms that could greatly improve the diagnosis, prognosis and treatment choice. The aim of
BELLISSIMO, TERESA, CARBONE, Antonio, DELLA ROCCA, Carlo, DI CARLO, ANGELINA, FAZI, Francesco, PALLESCHI, GIOVANNI, PASTORE, ANTONIO LUIGI, PETROZZA, Vincenzo, PORTA, NATALE   +8 more
core   +2 more sources

Exon-skipping brain natriuretic peptide variant is overexpressed in failing myocardium and attenuates brain natriuretic peptide production in vitro [PDF]

, 2010
Original research[Abstract] Brain natriuretic peptide/natriuretic peptide precursor B (NPPB) is one of the most studied genes in relation to heart failure (HF) conditions.
Centeno, Alberto, Iglesias Reinoso, Raquel, López, Eduardo, Mikhailov, Alexander T., Torrado, Mario   +4 more
core   +2 more sources

IL28B is associated with outcomes of chronic HBV infection [PDF]

, 2015
Purpose The role of IL28B gene variants and expression in hepatitis B virus (HBV) infections are not well understood. Here, we evaluated whether IL28B gene expression and rs12979860 variations are associated with HBV outcomes.
Chi, Xiumei, Gao, Yanhang, Jiang, Jing, Li, Wanyu, Minuk, Gerald, Niu, Junqi, Pan, Yu, Shi, Xiaodong, Xu, Damo, Yang, Chen, Zhang, Manna, Zhong, Jin   +11 more
core   +1 more source

Detection of economically important viruses in boar semen by quantitative RealTime PCR™ technology

Journal of Virological Methods, 2004
The objective of this study was to develop quantitative real-time polymerase chain reaction (ReTi-PCR) tests for the detection of five economically important viruses in swine semen namely, pseudorabies virus (PRV), classical swine fever virus (CSFV), foot-and-mouth disease virus (FMDV), swine vesicular disease virus (SVDV), and porcine reproductive and
van Rijn, P.A., Wellenberg, G.J., van der Hakze-van der Honing, R.W., Jacobs, C.E., Moonen, P.L.J.M., Feitsma, H.   +5 more
openaire   +3 more sources