Results 251 to 260 of about 178,419 (318)

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

The Foregone Earnings From Child Rearing Revisited [PDF]

open access: yes
Deborah Mitchell   +4 more
core  

The burden of disease in Swiss pork production. [PDF]

open access: yesFront Vet Sci
Savioli G, Kümmerlen D, Thomann B.
europepmc   +1 more source

Postpartum adversity in rats creates a hypervigilant maternal state through selective salience-circuit recruitment. [PDF]

open access: yesNeurobiol Stress
Song M   +9 more
europepmc   +1 more source

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