Results 131 to 140 of about 3,703,656 (252)

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Beyond Standard Defaults: How Reason Defaults Promote Green Product Purchase Through Reduced Psychological Reactance. [PDF]

Behav Sci (Basel)
Ge W, Jiang Y.
europepmc   +1 more source

Introduction:Experiencing Liveness in Contemporary Performance

, 2017
Lindelof, Anja Mølle, Reason, Matthew
core   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Reason : free minds and free markets

, 1994

core   +5 more sources

Correction: From animal models to NAMs: a paradigm shift in developmental immunotoxicity testing. [PDF]

Arch Toxicol
Iulini M, de Bruijn V, Hurem S, Nygaard UC, Kerdine-Römer S, Spruck C, Tigges J, Vandebriel R, Corsini E.   +8 more
europepmc   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Gender-Affirming Surgery as a Treatment Option for Gender Dysphoria in Adults: A Systematic Review of Ethical Reasons. [PDF]

Healthcare (Basel)
Moolekkudiyil Baby B, De Maeseneer Y, Dierickx K.   +2 more
europepmc   +1 more source

The Rhetoric of Reason Writing and the Attractions of Argument

Intro -- Contents -- Acknowledgments -- Introduction -- Part One: Philosophy, Rhetoric, and Argumentation -- Chapter 1. The End of Philosophy and the Resurgence of Rhetoric -- The Aims of a Rhetoric of Reason -- The Philosophical Context -- After ...
Crosswhite, James R.
core  

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source