Results 111 to 120 of about 3,703,656 (252)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
"The Sleep of Reason:" A Video Installation by Bill Viola
, 1991 Photograph of the exhibition "'The Sleep of Reason:' A Video Installation by Bill Viola," November 14, 1991-February 9, 1992 held at the Dallas Museum of ...
Dallas Museum of Art
core +2 more sources
Kantian Reflections on Conceptual Limits [PDF]
Public ReasonThis paper reflects on Kantian exchanges between A. W. Moore and Sorin Baiasu. After briefly situating their exchange, I highlight Baiasu’s clarification regarding Kant’s distinction between knowledge and cognition. Although convincing, I suggest that
Zachary Vereb
doaj
, 2013 Information about patients’ adherence to therapy represents a primary issue in Parkinson’s disease (PD) management. To perform the linguistic validation of the Italian version of the self-rated 8-Item Morisky Medical Adherence Scale (MMAS-8) and to ...
Antonini A. +10 more
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Heritage and Hate: Teaching Confederate Monuments with Archives
Panorama, 2019 Akela Reason
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Good and Evil in the Interior Voluntary Act : S.T.I-II,q,19 [PDF]
, 2002 P(論文)In the Summa Theologiae, I-II, q.19, Thomas Aquinas discusses good and evil in the interior voluntary act. According to Thomas, man's will is moved by the object, which his intellect presents to it.
OHARA, Taku +3 more
core
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source