Results 111 to 120 of about 3,262,397 (309)
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Epistemological Issues in the Theory of Equality of Opportunity [PDF]
Public ReasonEOp (Equality of opportunity) is an algorithm for measuring the degree of opportunity equality in a society. The researcher must identify the kind of advantage of concern (e.g., income , life expectancy, wage earning capacity), and what circumstances ...
John E. Roemer
doaj
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
On the Meaning of Democracy in the European Union [PDF]
Public ReasonUsing some of Immanuel Kant's ontological categories, and the categories of meaning, the author shows some methodological difficulties met when defining democracy in EU law: the difficulties with categorization because there do not exist complete systems
Jaanika Erne
doaj
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Speaking Truth to Power? A Foucauldian Theory of Whistleblowing in A Nihilistic World [PDF]
Public ReasonThis paper aims to propose a novel account of whistleblowing. Whistleblowing is seen as “speaking truth to power”. But if there is no truth outside power, as in our post-truth age, whistleblowing loses its meaning.
Lingyu Jing
doaj
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Resting in the Court of Reason: Kant's Resolution to the Antinomy of Pure Reason
, 2007 Kant attributes the power to awaken one from dogmatic slumber to skepticism and to the antinomy of pure reason; in his accounts of his own awakening and the origin of the critical philosophy, he credits the antinomy and his memory of David Hume.
Alexander, Sarah Ann
core +1 more source