Results 101 to 110 of about 3,703,656 (252)
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
On the Meaning of Democracy in the European Union [PDF]
Public ReasonUsing some of Immanuel Kant's ontological categories, and the categories of meaning, the author shows some methodological difficulties met when defining democracy in EU law: the difficulties with categorization because there do not exist complete systems
Jaanika Erne
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FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Speaking Truth to Power? A Foucauldian Theory of Whistleblowing in A Nihilistic World [PDF]
Public ReasonThis paper aims to propose a novel account of whistleblowing. Whistleblowing is seen as “speaking truth to power”. But if there is no truth outside power, as in our post-truth age, whistleblowing loses its meaning.
Lingyu Jing
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Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Review of Rodney A. Brooks : Intelligence Without Reason
, 1998 This paper will provide an overview of Rodney A. Brooks' Intelligence Without Reason, followed by a discussion of Oren Etzioni's and Michael Coen's critiques of the paper. Finally, my own thoughts will conclude the report.
Eric Benzacar +2 more
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Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
, 2020 Title from PDF caption (viewed on April 5, 2021).This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.
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