Results 151 to 160 of about 9,923,749 (308)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Success rates of trial of labor after cesarean delivery: the impact of prior vaginal deliveries on outcomes. [PDF]

Arch Gynecol Obstet
Bashan Y, Shalev Maman E, Rosenberg R, Yekel Y, Weintraub A, Duvdevani NR, Pasternak Y.   +6 more
europepmc   +1 more source

Reason for Everything [PDF]

, 2018
Shadoan, Katelyn
core   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Reason and Reasoning

, 1999
In the time of Descartes, philosophers on both sides of the English Channel inhabited the same universe of discourse, were concerned with the same range of questions and argued about them in mutually intelligible ways. Descarte's own central concern, of course, was questions ofcertainty, knowledge and truth; as Anthony Kenny has put it, "his whole ...
openaire   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Nurses' Decisions to Press Charges Against Hypothetical Patients Who Exhibit Violent Behavior. [PDF]

Nurs Rep
Copeland D, Tipton S, Culter D, Potter M.   +3 more
europepmc   +1 more source

Reasons for Reasons

Abstract This chapter describes the role of reasons for concept use, showing how they allow us to answer the authority question without crowding out other kinds of reasons that transcend preoccupation with human concerns or with the instrumentality of concepts.
openaire   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Comparing ChatGPT and DeepSeek for Assessment of Multiple-Choice Questions in Orthopedic Medical Education: Cross-Sectional Study. [PDF]

JMIR Form Res
Anusitviwat C, Suwannaphisit S, Bvonpanttarananon J, Tangtrakulwanich B.   +3 more
europepmc   +1 more source