Results 131 to 140 of about 785,607 (304)

Sino- Japanese relationship - Conflict reasons under historical perspective

open access: yes, 2017
The bilateral relationship between China and Japan has often been marked by mistrust and enmitiy. This thesis focuses on the 21st century and discusses conflict reasons, based on the shared history of both ...
Jeschke, Janine
core  

ENGLISH-INTERNATIONAL HUMANITARIAN LAW IN A SHARIA DOMNINATED ISLAMIC CONTEXT: ARMED CONFLICT IN PAKISTAN

open access: yesدی اسکالر, 2019
The applicability of International Humanitarian Law (IHL) to the non-international armed conflicts is questioned due to various reasons, mainly the complex nature of such conflicts fulfilling the criteria set under IHL.
Faiz Bakhsh   +2 more
doaj  

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Shifting Paradigms: Exploring the Reasons for Staff Care and ‘The Duty of Care’ in International Peace and Conflict Work

open access: yes, 2023
Peace and conflict workers, peace educators and other humanitarian, aid and social workers are engaged in responsible and challenging contexts.  There are a lot of reasons, why they should be accompanied, supported and counseled during their work ...
Pastoors, Daniela
core  

Vivre entre les frontières intérieures de l’Irak. Quel devenir pour les derniers déplacés de Mossoul ?

open access: yesLes Cahiers d’EMAM
The political and territorial fragmentation of Iraq is at the origin of territorial oddities. Some parts of Iraqi territory are controlled by armed non-State actors (militias) supported by tutelary powers, usually competitors.
Cyril Roussel
doaj  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Folly to the Greeks: Good Reasons to Give Up Reasons

open access: yes, 2012
Good reasons to "give up reason" are (i) naturalistic reasons that downplay the likely effectiveness of human mentation - these lead to contradiction if naturalism itself is reckoned “really true”; (ii) there are pragmatic reasons to license and enjoy ...
Stephen R. L. Clark
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

From reasons to rules

open access: yes
What reasons for action do we have? When do our reasons conflict with each other? How are these practical conflicts resolved? And, most importantly, what ought we do in the face of such conflicts?
Vassiliou, Andreas
core   +1 more source

Is the European Union Fighting the War for Children? The EU Policy on the Rights of Children Affected by Armed Conflict. College of Europe EU Diplomacy Paper 8/2010 [PDF]

open access: yes, 2010
More than two million child soldiers have died in conflicts throughout the world. The official response to this phenomenon, which involved devising international conventions, proved to be inadequate.
Kanli, Athanasia.
core  

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