Results 41 to 50 of about 9,013 (178)

New approaches for unravelling reassortment pathways [PDF]

BMC Evolutionary Biology, 2013
AbstractBackgroundEvery year the human population encounters epidemic outbreaks of influenza, and history reveals recurring pandemics that have had devastating consequences. The current work focuses on the development of a robust algorithm for detecting influenza strains that have a composite genomic architecture.
Mcinerney, James, Svinti, Victoria, Cotton, James A, McInerney, James O   +3 more
openaire   +3 more sources

In Situ Hybridization and RT‐PCR Detection of Nervous Necrosis Virus in Fourfinger Threadfin, Eleutheronema tetradactylum, in Taiwan

Journal of Fish Diseases, EarlyView.
ABSTRACT Between April and July 2020, suspected outbreaks of nervous necrosis virus (NNV) infection were observed in fourfinger threadfin (Eleutheronema tetradactylum) fingerling hatcheries in Pingtung County, southern Taiwan. Affected fish exhibited spiral swimming behaviour and abdominal distension, resulting in mortality rates between 50% and 100 ...
Chia‐Yu Hsieh, Shang‐Ting Wu, Chun‐Ying Lin   +2 more
wiley   +1 more source

In vivo reassortment of influenza viruses.

Acta Biochimica Polonica, 2014
The genetic material of influenza A virus consists of eight negative-sense RNA segments. Under suitable conditions, the segmented structure of the viral genome allows an exchange of the individual gene segments between different strains, causing formation of new reassorted viruses.
Urbaniak, Kinga, Iwona Markowska-Daniel
openaire   +3 more sources

Feathers and flu: identifying data gaps in avian influenza host dynamics to prioritize wildlife conservation Plumas y gripe: identificación de datos faltantes en la dinámica de hospedadores de la influenza aviar para priorizar la conservación de la vida silvestre

Wildlife Monographs, Volume 225, Issue 1, September 2026.
We describe the host response continuum for highly pathogenic avian influenza viruses (HPAIV), including the continuum of host responses to HPAIV infection and exposure based on the primary axis of host competence, ability to infect other hosts, and host vulnerability.
Johanna A. Harvey, Matthew Gonnerman, Shenglai Yin, Cody M. Kent, Joshua Cullen, Jeffery D. Sullivan, Jonathan B. Dain, Nichola J. Hill, Diann J. Prosser, Jennifer M. Mullinax   +9 more
wiley   +1 more source

Analysis of reassortant and intragenic recombination in Cypovirus [PDF]

Virology Journal, 2020
AbstractCypoviruses (CPVs) are RNA viruses with segmented double-stranded genome and major pathogens of various insects, including economic insects like silkworms and pest insects for agricultural crops and forests. Genome reassortment and recombination are common phenomenon for viruses as a mechanism to expand host range and increase virulence. In the
Zhendong Zhang, Ning Li, Chengxiang Hou, Kun Gao, Xudong Tang, Xijie Guo   +5 more
openaire   +3 more sources

Two Lineages of DS‐1‐Like G3P[8] Human Rotaviruses in Sabah, Malaysia: Genetic Diversity and Evidence of Reassortment

Journal of Medical Virology, Volume 98, Issue 8, August 2026.
ABSTRACT Group A rotavirus (RVA) genotype G3P[8] strains typically carry a Wa‐like genomic backbone, but DS‐1‐like G3P[8] reassortants have disseminated globally since 2013. In Sabah, Malaysia, surveillance in 2018–2019 identified frequent G3P[8] strains with a short RNA electropherotype, consistent with DS‐1‐like backbones.
Yuki Akari, Lia Natasha Amit, Jecelyn Leaslie John, Daisuke Mori, Abraham Zefong Chin, Andau Konodan Mosiun, Saori Fukuda, Maurine Mumo Mutua, Ibuki Sato, Yoshimasa Maeno, Kamruddin Ahmed, Satoshi Komoto   +11 more
wiley   +1 more source

The Wells–Riley Model Revisited II: Parameter Uncertainty and Population Heterogeneity

Risk Analysis, Volume 46, Issue 8, August 2026.
ABSTRACT In this work, we revisit the Wells–Riley model, which has been widely used to estimate airborne infection risk in indoor settings. In particular, we consider a probabilistic (i.e., “stochastic”) framework of the Wells–Riley model which allows one to quantify infection risk in terms of the per‐capita probability of infection for each ...
Marcus Marshall, Alexander J. Edwards, Dominique Pinnell, Marco‐Felipe King, Catherine J. Noakes, Nazif Elaldi, Grant Lythe, Martín López‐García   +7 more
wiley   +1 more source

A Potential Nervous Necrosis Virus (NNV) Live Vaccine for Sole Obtained by Genomic Modification

Animals
Viral Encephalopathy and Retinopathy (VER) is a neurological infectious fish disease that causes vacuolization and necrosis in the central nervous system, which lead to swimming abnormalities and, generally, host death in the early stages of development.
Lucía Vázquez-Salgado, Sandra Souto, José G. Olveira, Isabel Bandín   +3 more
doaj   +1 more source

Lymphoid‐Tissue‐on‐Chip Recapitulates Human Antibody Responses In Vitro

Advanced Science, Volume 13, Issue 37, 3 July 2026.
The presented lymphoid‐tissue‐on‐chip system allows culture of primary human tonsil cells at organotypic high density under perfusion for up to 4 weeks, emulates immune response to soluble vaccines and vaccination via peripheral antigen‐presenting cells and represents a useful tool to assess cellular interactions during homeostasis, immune responses ...
Claudia Teufel, Anna‐Sophie Schlemmer, Andrea W. Eiken, Zachary W. Wagoner, Dennis Vöhringer, Lena Christ, Alex Dulovic, Patrick Marsall, Madeleine Fandrich, Eduardo J. S. Brás, Julia Marzi, Friederike Bärhold, Julia Philipp, Sven Becker, Lisa E. Wagar, Peter Loskill   +15 more
wiley   +1 more source

Immunogenicity of a Multi‐Epitope Influenza Composite Peptide Vaccine Targeting Human, Swine, and Avian Viruses: Advancing Pandemic Preparedness

Influenza and Other Respiratory Viruses, Volume 20, Issue 7, July 2026.
ABSTRACT Background The emergence of novel reassortant influenza A virus strains and zoonotic transmission to the human population is a critical factor in the development of a global pandemic, as exemplified by the 2009 swine flu pandemic and the ongoing threat of an H5N1 avian flu pandemic.
Nimisha Rikhi, Clara J. Sei, Kellie A. Fraser, Kevin Muema, Aba Assiaw‐Dufu, Richard F. Schuman, Gerald W. Fischer   +6 more
wiley   +1 more source