Results 61 to 70 of about 15,555 (198)
Reassortment of genetic segments between and within influenza B lineages (Victoria and Yamagata) has been shown to generate novel reassortants with unique genetic characteristics.
Xiang Yong Oong +7 more
doaj +1 more source
ABSTRACT Introduction Swine may act as ‘epidemiological bridges’ and reservoirs for the emergence of novel zoonotic influenza viruses with pandemic potential. While bidirectional exchange of influenza A viruses at the swine–human interface is well recognised, data on the extent of interspecies transmission are limited.
Solveig Jore +7 more
wiley +1 more source
Development of a three‐step synthesis and replacement of the cycloheptyl moiety in cycloheptathiophene‐3‐carboxamide derivatives revealed how thiophene C‐5 substitutions modulate PA–PB1 inhibition, antiviral potency, and water solubility. The phenyl analog 9 delivered sub‐µM potency across multiple IV strains, while the methyl analog 5 achieved the ...
Tommaso Felicetti +8 more
wiley +1 more source
ABSTRACT Introduction Influenza A viruses (IAVs) are responsible for respiratory infections in a wide range of species, including birds, swine and humans. The role of wild boar (Sus scrofa) in IAV epidemiology remains underexplored. Here, we present a longitudinal serologic and virologic surveillance study of wild boars in Spain from 2015 to 2023 ...
Paloma Encinas +8 more
wiley +1 more source
Vector‐borne diseases‐knowledge maps
Abstract This scientific report provides a structured overview of the main characteristics of 25 selected vector‐borne diseases (VBDs) of potential relevance for the EU, including 12 diseases listed under the Animal Health Law (AHL) and 13 non‐listed diseases.
European Food Safety Authority (EFSA) +7 more
wiley +1 more source
Attenuation of Influenza a Virus into Live Vaccines Through C‐End Degrons
Naturally occurring C‐end degrons are exploited to design proteolysis‐targeting live attenuated influenza vaccines. C‐end degron tagging of viral M1 protein promotes proteasome‐dependent degradation, resulting in robust attenuation in host cells while permitting scalable production in engineered cells.
Ping Wang +14 more
wiley +1 more source
Novel Swine Influenza Virus Reassortants in Pigs, China
During swine influenza virus surveillance in pigs in China during 2006–2009, we isolated subtypes H1N1, H1N2, and H3N2 and found novel reassortment between contemporary swine and avian panzootic viruses.
Yuhai Bi +12 more
doaj +1 more source
Highly pathogenic avian influenza (HPAI) viruses of subtype H5Nx caused outbreaks in poultry, captive birds, and wild birds in the Netherlands between October 2020 and June 2021. The full genome sequences of 143 viruses were analyzed.
Marc Engelsma +4 more
doaj +1 more source
ABSTRACT Rotavirus remains one of the major causes of childhood gastroenteritis despite the widespread introduction of rotavirus vaccines. Here, we report a sibling cluster of three children hospitalized with fever, vomiting, and diarrhea. Two unvaccinated siblings (11 years 9 months and 10 years 1 month) developed severe gastroenteritis with profuse ...
Ahmad Syatir Tahar +3 more
wiley +1 more source
ABSTRACT Background Epidemiological surveillance of influenza D virus (IDV) has gained increased priority following recent serological findings indicating its potential zoonosis in humans. In this context, it is crucial to develop strong, reproducible, reliable and scalable immunological assays that can be quickly implemented in the surveillance of new
Maria Giovanna Marotta +10 more
wiley +1 more source

