Results 51 to 60 of about 22,607 (211)

The effective rate of influenza reassortment is limited during human infection.

PLoS Pathogens, 2017
We characterise the evolutionary dynamics of influenza infection described by viral sequence data collected from two challenge studies conducted in human hosts. Viral sequence data were collected at regular intervals from infected hosts.
Ashley Sobel Leonard, Micah T McClain, Gavin J D Smith, David E Wentworth, Rebecca A Halpin, Xudong Lin, Amy Ransier, Timothy B Stockwell, Suman R Das, Anthony S Gilbert, Rob Lambkin-Williams, Geoffrey S Ginsburg, Christopher W Woods, Katia Koelle, Christopher J R Illingworth   +14 more
doaj   +1 more source

Terminal reassortment drives the quantum evolution of type III effectors in bacterial pathogens. [PDF]

PLoS Pathogens, 2006
Many bacterial pathogens employ a type III secretion system to deliver type III secreted effectors (T3SEs) into host cells, where they interact directly with host substrates to modulate defense pathways and promote disease.
John Stavrinides, Wenbo Ma, David S Guttman   +2 more
doaj   +1 more source

Evolution of Avian Influenza Virus (H3) with Spillover into Humans, China

Emerging Infectious Diseases, 2023
The continuous evolution of avian influenza viruses (AIVs) of subtype H3 in China and the emergence of human infection with AIV subtype H3N8 highlight their threat to public health.
Jiaying Yang, Ye Zhang, Lei Yang, Xiyan Li, Hong Bo, Jia Liu, Min Tan, Wenfei Zhu, Yuelong Shu, Dayan Wang   +9 more
doaj   +1 more source

A synthetic biology approach for a vaccine platform against known and newly emerging serotypes of bluetongue virus [PDF]

, 2014
Bluetongue is one of the major infectious diseases of ruminants and is caused by Bluetongue virus (BTV), an arbovirus existing in nature in at least 26 distinct serotypes. Here, we describe the development of a vaccine platform for BTV.
Brunet, Silvie, Hamers, Claude, Hudelet, Pascal, Nunes, Sandro Filipe, Palmarini, Massimo, Ratinier, Maxime, Shaw, Andrew   +6 more
core   +2 more sources

Whole-Genome Analyses Identifies Multiple Reassortant Rotavirus Strains in Rwanda Post-Vaccine Introduction

Viruses, 2021
Children in low-and middle-income countries, including Rwanda, experience a greater burden of rotavirus disease relative to developed countries. Evolutionary mechanisms leading to multiple reassortant rotavirus strains have been documented over time ...
Sebotsana Rasebotsa, Jeannine Uwimana, Milton T. Mogotsi, Kebareng Rakau, Nonkululeko B. Magagula, Mapaseka L. Seheri, Jason M. Mwenda, M. Jeffrey Mphahlele, Saheed Sabiu, Richard Mihigo, Leon Mutesa, Martin M. Nyaga   +11 more
doaj   +1 more source

A Retrospective Cross‐Sectional Study (2009–2023): Exploring Influenza A(H1N1)pdm09 Antibody Time Series in Humans and Swine and Vaccine Coverage in Two Target Groups

Zoonoses and Public Health, Volume 73, Issue 4, Page 336-347, June 2026.
ABSTRACT Introduction Swine may act as ‘epidemiological bridges’ and reservoirs for the emergence of novel zoonotic influenza viruses with pandemic potential. While bidirectional exchange of influenza A viruses at the swine–human interface is well recognised, data on the extent of interspecies transmission are limited.
Solveig Jore, Ragnhild Tønnessen, Carl Andreas Grøntvedt, Kjersti Rydland, Anna Germundsson Hauge, Olav Hungnes, Anja Bråthen Kristoffersen, Even Fossum   +7 more
wiley   +1 more source

Influenza virus [PDF]

, 2018
No abstract ...
Hutchinson, Edward C.
core   +1 more source

Longitudinal Surveillance of Influenza A Virus Exposure in Wild Boars (Sus scrofa) in Spain (2015–2023): Serologic and Virologic Evidence of Subtype Infections and H5N1 Spillover Risk

Zoonoses and Public Health, Volume 73, Issue 3, Page 191-204, May 2026.
ABSTRACT Introduction Influenza A viruses (IAVs) are responsible for respiratory infections in a wide range of species, including birds, swine and humans. The role of wild boar (Sus scrofa) in IAV epidemiology remains underexplored. Here, we present a longitudinal serologic and virologic surveillance study of wild boars in Spain from 2015 to 2023 ...
Paloma Encinas, Aitor Nogales, Estela Escribano‐Romero, M. Ángeles Martín del Burgo, Jorge Ramón López‐Olvera, José Enrique Granados, Gregorio Mentaberre, Adolfo García‐Sastre, Gustavo del Real   +8 more
wiley   +1 more source

Analyses and Insights into Genetic Reassortment and Natural Selection as Key Drivers of Piscine orthoreovirus Evolution

Viruses
Piscine orthoreovirus (PRV) is a pathogen that causes heart and skeletal muscle inflammation in Salmo salar and has also been linked to circulatory disorders in other farmed salmonids, such as Oncorhynchus kisutch and Oncorhynchus mykiss. The virus has a
Laura Solarte-Murillo, Humberto Reyes, Loreto Ojeda, Juan G. Cárcamo, Juan Pablo Pontigo, Carlos A. Loncoman   +5 more
doaj   +1 more source

Trends of influenza B during the 2010–2016 seasons in 2 regions of north and south Italy: The impact of the vaccine mismatch on influenza immunisation strategy [PDF]

, 2018
Influenza A and B viruses are responsible for respiratory infections, representing globally seasonal threats to human health. The 2 viral types often co-circulate and influenza B plays an important role in the spread of infection.
Alicino C., Ansaldi F., Calamusa G., Canepa P., Colomba G. M. E., Orsi A., Pojero F., Tramuto F., Trucchi C., Vitale F.   +9 more
core   +1 more source