Results 31 to 40 of about 16,546 (197)

Theoretical risk of genetic reassortment should not impede development of live, attenuated Rift Valley fever (RVF) vaccines commentary on the draft WHO RVF Target Product Profile

Vaccine: X, 2020
In November 2019, The World Health Organization (WHO) issued a draft set of Target Product Profiles (TPPs) describing optimal and minimally acceptable targets for vaccines against Rift Valley fever (RVF), a Phlebovirus with a three segmented genome, in ...
Thomas P. Monath, Jeroen Kortekaas, Douglas M. Watts, Rebecca C. Christofferson, Angelle Desiree LaBeaud, Brian B Gowen, Clarence J. Peters, Darci R. Smith, Robert Swanepoel, John C. Morrill, Thomas G. Ksiazek, Phillip R Pittman, Stuart T. Nichol, Brian H. Bird, George Bettinger   +14 more
doaj   +1 more source

Long-term surveillance reveals hybridization by nuclear reassortment and intercontinental spread as major evolutionary drivers in wheat yellow rust. [PDF]

New Phytol
Documented incursions of Puccinia striiformis 2009–2023 based on sequential resampling of MLGs/pathogen races on different continents. Summary Evolutionary forces affecting crop pathogens, including hybridization and long‐distance dispersal (LDD), may have strong implications for food security and sustainable plant disease control at global scales ...
Hovmøller MS, Thach T, Rodriguez-Algaba J, Hansen JG, Meyer M, Hodson DP, Nazari K, Park RF, Tam R, Möller M, Schwessinger B, Rathjen JP, Silva P, Riella V, Justesen AF.   +14 more
europepmc   +2 more sources

Influenza A virus reassortment in mammals gives rise to genetically distinct within-host subpopulations

Nature Communications, 2022
Virus reassortment drives genetic diversity and evolution and is governed by intra-host dynamics that are less well understood. Here, the authors characterise the within-host dynamics of influenza A virus reassortment in swine, ferrets and guinea pigs ...
Ketaki Ganti, Anish Bagga, Silvia Carnaccini, Lucas M. Ferreri, Ginger Geiger, C. Joaquin Caceres, Brittany Seibert, Yonghai Li, Liping Wang, Taeyong Kwon, Yuhao Li, Igor Morozov, Wenjun Ma, Juergen A. Richt, Daniel R. Perez, Katia Koelle, Anice C. Lowen   +16 more
doaj   +1 more source

Intrasubtype reassortments cause adaptive amino acid replacements in H3N2 influenza genes. [PDF]

PLoS Genetics, 2014
Reassortments and point mutations are two major contributors to diversity of Influenza A virus; however, the link between these two processes is unclear.
Alexey D Neverov, Ksenia V Lezhnina, Alexey S Kondrashov, Georgii A Bazykin   +3 more
doaj   +1 more source

Frequency of influenza H3N2 intra-subtype reassortment: attributes and implications of reassortant spread [PDF]

BMC Biology, 2016
De plus en plus de preuves suggèrent que le réassortiment de la grippe contribue non seulement à l'émergence de nouvelles pandémies humaines, mais joue également un rôle important dans les épidémies de grippe saisonnière, la gravité de la maladie, l'évolution et l'efficacité des vaccins.
Irina Maljkovic Berry, Melanie C. Melendrez, Tao Li, Anthony W. Hawksworth, Gary T. Brice, Patrick J. Blair, Eric S. Halsey, Maya Williams, Stefan Fernandez, In‐Kyu Yoon, Leslie Edwards, Robert A. Kuschner, Xiangui Lin, Stephen J. Thomas, Richard G. Jarman   +14 more
openaire   +2 more sources

Influenza Virus Reassortment Is Enhanced by Semi-infectious Particles but Can Be Suppressed by Defective Interfering Particles.

PLoS Pathogens, 2015
A high particle to infectivity ratio is a feature common to many RNA viruses, with ~90-99% of particles unable to initiate a productive infection under low multiplicity conditions. A recent publication by Brooke et al.
Judith M Fonville, Nicolle Marshall, Hui Tao, John Steel, Anice C Lowen   +4 more
doaj   +1 more source

Analysis of reassortant and intragenic recombination in Cypovirus [PDF]

Virology Journal, 2020
AbstractCypoviruses (CPVs) are RNA viruses with segmented double-stranded genome and major pathogens of various insects, including economic insects like silkworms and pest insects for agricultural crops and forests. Genome reassortment and recombination are common phenomenon for viruses as a mechanism to expand host range and increase virulence. In the
Zhendong Zhang, Ning Li, Chengxiang Hou, Kun Gao, Xudong Tang, Xijie Guo   +5 more
openaire   +3 more sources

Reassortment plots and rates determined from plaque isolates.

, 2023
A. Reassortment plot of genotyped progeny isolated from each coinfection performed in this study. Genotypes for individual progeny are depicted as rows in each panel with columns indicating the genotype (i.e.
Sari Mäntynen (14701367), Courtney Mattson (9979043), David Gresham (148568), Bin Zhou (84959), Samuel L. Díaz Muñoz (14701370), Elodie Ghedin (8860), Ivy José (14701364), Ilechukwu Agu (14701361), A. J. Campbell (11021412), Tsui-Wen Chou (12453715), Kishana Y. Taylor (14701358)   +10 more
core   +1 more source

Widespread Reassortment Shapes the Evolution and Epidemiology of Bluetongue Virus following European Invasion.

PLoS Pathogens, 2015
Genetic exchange by a process of genome-segment 'reassortment' represents an important mechanism for evolutionary change in all viruses with segmented genomes, yet in many cases a detailed understanding of its frequency and biological consequences is ...
Kyriaki Nomikou, Joseph Hughes, Rachael Wash, Paul Kellam, Emmanuel Breard, Stéphan Zientara, Massimo Palmarini, Roman Biek, Peter Mertens   +8 more
doaj   +1 more source

In Vitro Reassortment between Endemic Bluetongue Viruses Features Global Shifts in Segment Frequencies and Preferred Segment Combinations

Microorganisms, 2021
Bluetongue virus (BTV) is an arthropod-borne pathogen that is associated with sometimes severe disease in both domestic and wild ruminants. Predominantly transmitted by Culicoides spp.
Jennifer Kopanke, Justin Lee, Mark Stenglein, Christie Mayo   +3 more
doaj   +1 more source