Results 31 to 40 of about 15,600 (199)

Frequency of influenza H3N2 intra-subtype reassortment: attributes and implications of reassortant spread [PDF]

BMC Biology, 2016
De plus en plus de preuves suggèrent que le réassortiment de la grippe contribue non seulement à l'émergence de nouvelles pandémies humaines, mais joue également un rôle important dans les épidémies de grippe saisonnière, la gravité de la maladie, l'évolution et l'efficacité des vaccins.
Irina Maljkovic Berry, Melanie C. Melendrez, Tao Li, Anthony W. Hawksworth, Gary T. Brice, Patrick J. Blair, Eric S. Halsey, Maya Williams, Stefan Fernandez, In‐Kyu Yoon, Leslie Edwards, Robert A. Kuschner, Xiangui Lin, Stephen J. Thomas, Richard G. Jarman   +14 more
openaire   +2 more sources

Estimating reassortment rates in co-circulating Eurasian swine influenza viruses [PDF]

, 2012
Swine have often been considered as a mixing vessel for different influenza strains. In order to assess their role in more detail, we undertook a retrospective sequencing study to detect and characterize the reassortants present in European swine and to ...
Pybus, OG, McCauley, J. W., Brown, I. H., Kellam, P., Leigh Brown, AJ, Lycett, S., Baillie, G., Baillie, G, Coulter, E, Brown, IH, Wood, JL, Lycett, S. J., Lycett, SJ, Coulter, E., McCauley, JW, Leigh Brown, A., Wood, J. L. N., Pybus, Oliver G., Bhatt, S., Kellam, P, N Wood, J., ?, ?, Wood, JLN, Pybus, Oliver, Brown Leigh, AJ, Bhatt, S, Brown, AJ Leigh, Brown, A. J. Leigh, Pybus, O. G., Brown, I., McCauley, J.   +30 more
core   +1 more source

Neuraminidase and hemagglutinin matching patterns of a highly pathogenic avian and two pandemic H1N1 influenza A viruses. [PDF]

PLoS ONE, 2010
BACKGROUND: Influenza A virus displays strong reassortment characteristics, which enable it to achieve adaptation in human infection. Surveying the reassortment and virulence of novel viruses is important in the prevention and control of an influenza ...
Yonghui Zhang, Xiaojing Lin, Guoqin Wang, Jianfang Zhou, Jian Lu, Honglan Zhao, Fengwei Zhang, Jia Wu, Chunqiong Xu, Ning Du, Zi Li, Ye Zhang, Xiaoyi Wang, Shengli Bi, Yuelong Shu, Hongning Zhou, Wenjie Tan, Xiaobing Wu, Zhihui Chen, Yue Wang   +19 more
doaj   +1 more source

Contrasting selective patterns across the segmented genome of bluetongue virus in a global reassortment hotspot [PDF]

, 2019
For segmented viruses, rapid genomic and phenotypic changes can occur through the process of reassortment, whereby co-infecting strains exchange entire segments creating novel progeny virus genotypes.
Singh, Karam P, Putty, Kalyani, Rao, Pavuluri P., Pavuluri P Rao, Kyriaki Nomikou, Yadav, Sarita, Narender Singh Maan, Mertens, Peter Paul Clement, Hegde, Nagendra R, Roman Biek, Y Krishna Jyothi, Reddy, Narasimha, Sarita Yadav, Maan, Sushila, Singh, Karam P., Jyothi, Y. Krishna, Rao, Pavuluri P, Maan, Narender Singh, Narasimha Reddy, Karam P Singh, Nagendra R Hegde, Singh, Karam Pal, Sushila Maan, Rao, Pavuluri Panduranga, Biek, Roman, Peter Mertens, Divakar Hemadri, Jyothi, Krishna Y.K., Hegde, Nagendra R., Jyothi, Y Krishna, Kalyani Putty, Mertens, Peter, Maude Jacquot Hemadri D, Nomikou, Kyriaki, Jacquot, Maude, Hemadri, Divakar, Hegde, Nagendra Ramachandra   +36 more
core   +1 more source

Influenza A virus reassortment in mammals gives rise to genetically distinct within-host subpopulations

Nature Communications, 2022
Virus reassortment drives genetic diversity and evolution and is governed by intra-host dynamics that are less well understood. Here, the authors characterise the within-host dynamics of influenza A virus reassortment in swine, ferrets and guinea pigs ...
Ketaki Ganti, Anish Bagga, Silvia Carnaccini, Lucas M. Ferreri, Ginger Geiger, C. Joaquin Caceres, Brittany Seibert, Yonghai Li, Liping Wang, Taeyong Kwon, Yuhao Li, Igor Morozov, Wenjun Ma, Juergen A. Richt, Daniel R. Perez, Katia Koelle, Anice C. Lowen   +16 more
doaj   +1 more source

Theoretical risk of genetic reassortment should not impede development of live, attenuated Rift Valley fever (RVF) vaccines commentary on the draft WHO RVF Target Product Profile

Vaccine: X, 2020
In November 2019, The World Health Organization (WHO) issued a draft set of Target Product Profiles (TPPs) describing optimal and minimally acceptable targets for vaccines against Rift Valley fever (RVF), a Phlebovirus with a three segmented genome, in ...
Thomas P. Monath, Jeroen Kortekaas, Douglas M. Watts, Rebecca C. Christofferson, Angelle Desiree LaBeaud, Brian B Gowen, Clarence J. Peters, Darci R. Smith, Robert Swanepoel, John C. Morrill, Thomas G. Ksiazek, Phillip R Pittman, Stuart T. Nichol, Brian H. Bird, George Bettinger   +14 more
doaj   +1 more source

Analysis of reassortant and intragenic recombination in Cypovirus [PDF]

Virology Journal, 2020
AbstractCypoviruses (CPVs) are RNA viruses with segmented double-stranded genome and major pathogens of various insects, including economic insects like silkworms and pest insects for agricultural crops and forests. Genome reassortment and recombination are common phenomenon for viruses as a mechanism to expand host range and increase virulence. In the
Zhendong Zhang, Ning Li, Chengxiang Hou, Kun Gao, Xudong Tang, Xijie Guo   +5 more
openaire   +3 more sources

Individual-specific reassortment rates. [PDF]

, 2017
A. Optimal reassortment rates inferred for individual subjects. Error bars, shown as horizontal lines, correspond to confidence intervals obtained via a likelihood ratio test. B. Correlation between the extent of evidence for a limited reassortment rate,
Ashley Sobel Leonard (2738740), Christopher W. Woods (104194), Xudong Lin (88866), Amy Ransier (3723697), David E. Wentworth (422363), Micah T. McClain (200348), Suman R. Das (236651), Anthony S. Gilbert (444037), Christopher J. R. Illingworth (108200), Katia Koelle (82611), Gavin J. D. Smith (150548), Rob Lambkin-Williams (444042), Rebecca A. Halpin (177954), Geoffrey S. Ginsburg (104197), Timothy B. Stockwell (249318)   +14 more
core   +1 more source

Intrasubtype reassortments cause adaptive amino acid replacements in H3N2 influenza genes. [PDF]

PLoS Genetics, 2014
Reassortments and point mutations are two major contributors to diversity of Influenza A virus; however, the link between these two processes is unclear.
Alexey D Neverov, Ksenia V Lezhnina, Alexey S Kondrashov, Georgii A Bazykin   +3 more
doaj   +1 more source

reassortment-simulation-and-reconstruction: publication release [PDF]

, 2015
<p>release for submission for peer review</p ...
Eric Ma
core   +1 more source