Results 31 to 40 of about 15,555 (198)

Estimating reassortment rates in co-circulating Eurasian swine influenza viruses [PDF]

, 2012
Swine have often been considered as a mixing vessel for different influenza strains. In order to assess their role in more detail, we undertook a retrospective sequencing study to detect and characterize the reassortants present in European swine and to ...
Pybus, OG, McCauley, J. W., Brown, I. H., Kellam, P., Leigh Brown, AJ, Lycett, S., Baillie, G., Baillie, G, Coulter, E, Brown, IH, Wood, JL, Lycett, S. J., Lycett, SJ, Coulter, E., McCauley, JW, Leigh Brown, A., Wood, J. L. N., Pybus, Oliver G., Bhatt, S., Kellam, P, N Wood, J., ?, ?, Wood, JLN, Pybus, Oliver, Brown Leigh, AJ, Bhatt, S, Brown, AJ Leigh, Brown, A. J. Leigh, Pybus, O. G., Brown, I., McCauley, J.   +30 more
core   +1 more source

Neuraminidase and hemagglutinin matching patterns of a highly pathogenic avian and two pandemic H1N1 influenza A viruses. [PDF]

PLoS ONE, 2010
BACKGROUND: Influenza A virus displays strong reassortment characteristics, which enable it to achieve adaptation in human infection. Surveying the reassortment and virulence of novel viruses is important in the prevention and control of an influenza ...
Yonghui Zhang, Xiaojing Lin, Guoqin Wang, Jianfang Zhou, Jian Lu, Honglan Zhao, Fengwei Zhang, Jia Wu, Chunqiong Xu, Ning Du, Zi Li, Ye Zhang, Xiaoyi Wang, Shengli Bi, Yuelong Shu, Hongning Zhou, Wenjie Tan, Xiaobing Wu, Zhihui Chen, Yue Wang   +19 more
doaj   +1 more source

Contrasting selective patterns across the segmented genome of bluetongue virus in a global reassortment hotspot [PDF]

, 2019
For segmented viruses, rapid genomic and phenotypic changes can occur through the process of reassortment, whereby co-infecting strains exchange entire segments creating novel progeny virus genotypes.
Singh, Karam P, Putty, Kalyani, Rao, Pavuluri P., Pavuluri P Rao, Kyriaki Nomikou, Yadav, Sarita, Narender Singh Maan, Mertens, Peter Paul Clement, Hegde, Nagendra R, Roman Biek, Y Krishna Jyothi, Reddy, Narasimha, Sarita Yadav, Maan, Sushila, Singh, Karam P., Jyothi, Y. Krishna, Rao, Pavuluri P, Maan, Narender Singh, Narasimha Reddy, Karam P Singh, Nagendra R Hegde, Singh, Karam Pal, Sushila Maan, Rao, Pavuluri Panduranga, Biek, Roman, Peter Mertens, Divakar Hemadri, Jyothi, Krishna Y.K., Hegde, Nagendra R., Jyothi, Y Krishna, Kalyani Putty, Mertens, Peter, Maude Jacquot Hemadri D, Nomikou, Kyriaki, Jacquot, Maude, Hemadri, Divakar, Hegde, Nagendra Ramachandra   +36 more
core   +1 more source

Theoretical risk of genetic reassortment should not impede development of live, attenuated Rift Valley fever (RVF) vaccines commentary on the draft WHO RVF Target Product Profile

Vaccine: X, 2020
In November 2019, The World Health Organization (WHO) issued a draft set of Target Product Profiles (TPPs) describing optimal and minimally acceptable targets for vaccines against Rift Valley fever (RVF), a Phlebovirus with a three segmented genome, in ...
Thomas P. Monath, Jeroen Kortekaas, Douglas M. Watts, Rebecca C. Christofferson, Angelle Desiree LaBeaud, Brian B Gowen, Clarence J. Peters, Darci R. Smith, Robert Swanepoel, John C. Morrill, Thomas G. Ksiazek, Phillip R Pittman, Stuart T. Nichol, Brian H. Bird, George Bettinger   +14 more
doaj   +1 more source

Analysis of reassortant and intragenic recombination in Cypovirus [PDF]

Virology Journal, 2020
AbstractCypoviruses (CPVs) are RNA viruses with segmented double-stranded genome and major pathogens of various insects, including economic insects like silkworms and pest insects for agricultural crops and forests. Genome reassortment and recombination are common phenomenon for viruses as a mechanism to expand host range and increase virulence. In the
Zhendong Zhang, Ning Li, Chengxiang Hou, Kun Gao, Xudong Tang, Xijie Guo   +5 more
openaire   +3 more sources

Influenza A virus reassortment in mammals gives rise to genetically distinct within-host subpopulations

Nature Communications, 2022
Virus reassortment drives genetic diversity and evolution and is governed by intra-host dynamics that are less well understood. Here, the authors characterise the within-host dynamics of influenza A virus reassortment in swine, ferrets and guinea pigs ...
Ketaki Ganti, Anish Bagga, Silvia Carnaccini, Lucas M. Ferreri, Ginger Geiger, C. Joaquin Caceres, Brittany Seibert, Yonghai Li, Liping Wang, Taeyong Kwon, Yuhao Li, Igor Morozov, Wenjun Ma, Juergen A. Richt, Daniel R. Perez, Katia Koelle, Anice C. Lowen   +16 more
doaj   +1 more source

Intrasubtype reassortments cause adaptive amino acid replacements in H3N2 influenza genes. [PDF]

PLoS Genetics, 2014
Reassortments and point mutations are two major contributors to diversity of Influenza A virus; however, the link between these two processes is unclear.
Alexey D Neverov, Ksenia V Lezhnina, Alexey S Kondrashov, Georgii A Bazykin   +3 more
doaj   +1 more source

Tempo and mode in the molecular evolution of influenza C [PDF]

, 2010
Influenza C contributes to economic damage caused by working days lost through absence or inefficiency and may occasionally cause an acute respiratory illness in a paediatric setting.
Gatherer, Derek, Derek Gatherer
core   +1 more source

Influenza Virus Reassortment Is Enhanced by Semi-infectious Particles but Can Be Suppressed by Defective Interfering Particles.

PLoS Pathogens, 2015
A high particle to infectivity ratio is a feature common to many RNA viruses, with ~90-99% of particles unable to initiate a productive infection under low multiplicity conditions. A recent publication by Brooke et al.
Judith M Fonville, Nicolle Marshall, Hui Tao, John Steel, Anice C Lowen   +4 more
doaj   +1 more source

Intrahost Dynamics of Influenza Virus Reassortment [PDF]

Journal of Virology, 2014
ABSTRACT The segmented nature of the influenza virus genome allows reassortment between coinfecting viruses. This process of genetic exchange vastly increases the diversity of circulating influenza viruses. The importance of reassortment to public health is clear from its role in the emergence of a number of epidemiologically ...
Hui, Tao, John, Steel, Anice C, Lowen
openaire   +2 more sources