Results 21 to 30 of about 16,930 (198)

Probing orthobunyavirus reassortment using Bunyamwera and Batai viruses as models.

PLoS Neglected Tropical Diseases
Reassortment is a critical evolutionary mechanism for segmented viruses, enabling the exchange of intact genome segments during co-infection and driving orthobunyavirus evolution; however, the molecular mechanisms underpinning this process remain unclear.
James M Bowen, Krista Gunter, Andrew M Lunel, Dorcus C A Omoga, Jennifer E Jones, Henry Giesel, W Paul Duprex, Natasha L Tilston   +7 more
doaj   +2 more sources

Reassortment patterns in Swine influenza viruses. [PDF]

PLoS Currents, 2009
Three human influenza pandemics occurred in the twentieth century, in 1918, 1957, and 1968. Influenza pandemic strains are the results of emerging viruses from non-human reservoirs to which humans have little or no immunity.
Raul Rabadan, Vladimir Trifonov, Khiabanian Hossein, Trifonov Vladimir, Khiabanian, Hossein, Hossein Khiabanian, Rabadan Raul, Trifonov, Vladimir, Rabadan, Raul   +8 more
core   +7 more sources

Terminal reassortment drives the quantum evolution of type III effectors in bacterial pathogens. [PDF]

PLoS Pathogens, 2006
Many bacterial pathogens employ a type III secretion system to deliver type III secreted effectors (T3SEs) into host cells, where they interact directly with host substrates to modulate defense pathways and promote disease.
John Stavrinides, Wenbo Ma, David S Guttman   +2 more
doaj   +2 more sources

Rift Valley Fever Phlebovirus Reassortment Study in Sheep [PDF]

Viruses
Rift Valley fever (RVF) in ungulates and humans is caused by a mosquito-borne RVF phlebovirus (RVFV). Live attenuated vaccines are used in livestock (sheep and cattle) to control RVF in endemic regions during outbreaks.
Velmurugan Balaraman, Sabarish V. Indran, In Joong Kim, Jessie D. Trujillo, David A. Meekins, Vinay Shivanna, Michelle D. Zajac, Kinga Urbaniak, Igor Morozov, Sun-Young Sunwoo, Bonto Faburay, Klaus Osterrieder, Natasha N. Gaudreault, William C. Wilson, Juergen A. Richt   +14 more
doaj   +3 more sources

Characterizing the Core Internal Gene Pool of H9N2 Responsible for Continuous Reassortment With Other Influenza A Viruses

Frontiers in Microbiology, 2021
Reassortment among avian influenza viruses is the main source of novel avian influenza virus subtypes. Studies have shown that the H9N2 virus often donates internal segments to generate novel reassortant avian influenza viruses, acting as a reassortment ...
Haoyi Yang, Haoyi Yang, Mingda Hu, Boqian Wang, Yuan Jin, Xingfei Gong, Xingfei Gong, Long Liang, Junjie Yue, Wei Chen, Hongguang Ren   +10 more
doaj   +1 more source

Epidemiological and Phylogenetic Analysis of Reassorted H10Nx Avian Influenza Viruses in Guangdong Province, China. [PDF]

Influenza Other Respir Viruses
ABSTRACT Aims H10 subtype avian influenza viruses circulate widely among wild and domestic birds worldwide. These viruses have crossed species barriers to infect mammals, including humans, with cases of H10N3, H10N5 and H10N8 reported. During active surveillance in Guangdong Province, China, between 2023 and 2025, we isolated 10 H10Nx influenza A ...
Liu J, Zhang Q, Xiang H, Li Y, Liu J, Yao Q, Gao Y, Ge Y.   +7 more
europepmc   +2 more sources

melibrun/Concatenation-of-segmented-viral-genomes-for-reassortment-analysis: archiving with Zenodo

, 2023
Concatenation of segmented viral genomes for reassortment ...
Ivanova Sasha
core   +1 more source

Development of reassortant influenza vaccines: classical reassortment or reverse genetics?

Russian Journal of Infection and Immunity, 2023
An important feature of influenza vaccines, which distinguishes them from other immunobiological preparations, is that they have no fixed composition. Due to the constant influenza virus antigenic variability, production facilities require timely supply with relevant vaccine strains undoable due to the lack of proper method for the convenient, rapid ...
Irina V. Kiseleva, Larisa G. Rudenko
openaire   +1 more source

Reassortment frequency by strain.

, 2023
A. Reassortment frequencies by strain, calculated from genotyping plaque isolates in ten experimental coinfections. Because reassortment frequency is pairwise property the same reassortment frequencies (points) appear in multiple strains, this is ...
Sari Mäntynen (14701367), Courtney Mattson (9979043), David Gresham (148568), Bin Zhou (84959), Samuel L. Díaz Muñoz (14701370), Elodie Ghedin (8860), Ivy José (14701364), Ilechukwu Agu (14701361), A. J. Campbell (11021412), Tsui-Wen Chou (12453715), Kishana Y. Taylor (14701358)   +10 more
core   +1 more source

Reassortment Between Divergent Strains of Camp Ripley Virus (Hantaviridae) in the Northern Short-Tailed Shrew (Blarina brevicauda)

Frontiers in Cellular and Infection Microbiology, 2020
Genomic reassortment of segmented RNA virus strains is an important evolutionary mechanism that can generate novel viruses with profound effects on human and animal health, such as the H1N1 influenza pandemic in 2009 arising from reassortment of two ...
Schuyler W. Liphardt, Hae Ji Kang, Satoru Arai, Se Hun Gu, Joseph A. Cook, Richard Yanagihara   +5 more
doaj   +1 more source