Results 11 to 20 of about 15,555 (198)

New approaches for unravelling reassortment pathways [PDF]

BMC Evolutionary Biology, 2013
Background Every year the human population encounters epidemic outbreaks of influenza, and history reveals recurring pandemics that have had devastating consequences.
Svinti Victoria, Cotton James A, McInerney James O   +2 more
doaj   +6 more sources

Predicting Hotspots for Influenza Virus Reassortment [PDF]

Emerging Infectious Diseases, 2013
The 1957 and 1968 influenza pandemics, each of which killed ≈1 million persons, arose through reassortment events. Influenza virus in humans and domestic animals could reassort and cause another pandemic.
Trevon L. Fuller, Marius Gilbert, Vincent Martin, Julien Cappelle, Parviez Hosseini, Kevin Y. Njabo, Soad Abdel Aziz, Xiangming Xiao, Peter Daszak, Thomas B. Smith   +9 more
doaj   +5 more sources

Bayesian inference of reassortment networks reveals fitness benefits of reassortment in human influenza viruses [PDF]

Proceedings of the National Academy of Sciences, 2020
Reassortment is an important source of genetic diversity in seg-mented viruses and is the main source of novel pathogenic influenza viruses. Despite this, studying the reassortment process has been constrained by the lack of a coherent, model-based infer-
Dudas, Gytis,, Vaughan, T. G., Stadler, T., Stolz, U., Muller, N. F.   +4 more
core   +6 more sources

Revealing Reassortment in Influenza A Viruses with TreeSort [PDF]

Molecular Biology and Evolution
Abstract Reassortment among influenza A viruses (IAV) facilitates evolution and has been associated with interspecies transmission and pandemics. We introduce a novel tool called TreeSort that accurately identifies recent and ancestral reassortment events on datasets with thousands of IAV whole genomes.
Alexey Markin, Amy L Vincent, Tavis K Anderson   +2 more
exaly   +4 more sources

HopPER: an adaptive model for probability estimation of influenza reassortment through host prediction

BMC Medical Genomics, 2020
Background Influenza reassortment, a mechanism where influenza viruses exchange their RNA segments by co-infecting a single cell, has been implicated in several major pandemics since 19th century.
Rui Yin, Xinrui Zhou, Shamima Rashid, Chee Keong Kwoh   +3 more
doaj   +2 more sources

Rift Valley Fever Phlebovirus Reassortment Study in Sheep [PDF]

Viruses
Rift Valley fever (RVF) in ungulates and humans is caused by a mosquito-borne RVF phlebovirus (RVFV). Live attenuated vaccines are used in livestock (sheep and cattle) to control RVF in endemic regions during outbreaks.
Velmurugan Balaraman, Sabarish V. Indran, In Joong Kim, Jessie D. Trujillo, David A. Meekins, Vinay Shivanna, Michelle D. Zajac, Kinga Urbaniak, Igor Morozov, Sun-Young Sunwoo, Bonto Faburay, Klaus Osterrieder, Natasha N. Gaudreault, William C. Wilson, Juergen A. Richt   +14 more
doaj   +3 more sources

TreeKnit: Inferring ancestral reassortment graphs of influenza viruses. [PDF]

PLoS Computational Biology, 2022
When two influenza viruses co-infect the same cell, they can exchange genome segments in a process known as reassortment. Reassortment is an important source of genetic diversity and is known to have been involved in the emergence of most pandemic ...
Pierre Barrat-Charlaix, Timothy G Vaughan, Richard A Neher   +2 more
doaj   +2 more sources

Analyses and Insights into Genetic Reassortment and Natural Selection as Key Drivers of Piscine orthoreovirus Evolution

Viruses
Piscine orthoreovirus (PRV) is a pathogen that causes heart and skeletal muscle inflammation in Salmo salar and has also been linked to circulatory disorders in other farmed salmonids, such as Oncorhynchus kisutch and Oncorhynchus mykiss. The virus has a
Laura Solarte-Murillo, Humberto Reyes, Loreto Ojeda, Juan G. Cárcamo, Juan Pablo Pontigo, Carlos A. Loncoman   +5 more
doaj   +2 more sources

Reassortment patterns in Swine influenza viruses.

PLoS Currents, 2009
Three human influenza pandemics occurred in the twentieth century, in 1918, 1957, and 1968. Influenza pandemic strains are the results of emerging viruses from non-human reservoirs to which humans have little or no immunity.
Raul Rabadan, Vladimir Trifonov, Khiabanian Hossein, Trifonov Vladimir, Khiabanian, Hossein, Hossein Khiabanian, Rabadan Raul, Trifonov, Vladimir, Rabadan, Raul   +8 more
core   +6 more sources

Evidence of Vaccine-related Reassortment of Rotavirus, Brazil, 2008–2010

Emerging Infectious Diseases, 2013
Analysis of 27 rotavirus strains from vaccinated and unvaccinated children revealed reassortment events in 3 strains: a gene derived from a vaccine; a gene acquired from a circulating strain; and reassortment between circulating strains.
Tatiana Lundgren Rose, Marcelle Figueira Marques da Silva, Mariela Martinéz Goméz, Hugo Reis Resque, Maria Yury Travassos Ichihara, Eduardo de Mello Volotão, José Paulo Gagliardi Leite   +6 more
doaj   +2 more sources