Results 11 to 20 of about 16,930 (198)

Fitness cost of reassortment in human influenza. [PDF]

open access: yesPLoS Pathogens, 2017
Reassortment, which is the exchange of genome sequence between viruses co-infecting a host cell, plays an important role in the evolution of segmented viruses.
Mara Villa, Michael Lässig
doaj   +5 more sources

Predicting Hotspots for Influenza Virus Reassortment [PDF]

open access: yesEmerging Infectious Diseases, 2013
The 1957 and 1968 influenza pandemics, each of which killed ≈1 million persons, arose through reassortment events. Influenza virus in humans and domestic animals could reassort and cause another pandemic.
Trevon L. Fuller   +9 more
doaj   +6 more sources

New approaches for unravelling reassortment pathways [PDF]

open access: yesBMC Evolutionary Biology, 2013
Background Every year the human population encounters epidemic outbreaks of influenza, and history reveals recurring pandemics that have had devastating consequences.
Svinti Victoria   +2 more
doaj   +5 more sources

HopPER: an adaptive model for probability estimation of influenza reassortment through host prediction

open access: yesBMC Medical Genomics, 2020
Background Influenza reassortment, a mechanism where influenza viruses exchange their RNA segments by co-infecting a single cell, has been implicated in several major pandemics since 19th century.
Rui Yin   +3 more
doaj   +2 more sources

Bayesian inference of reassortment networks reveals fitness benefits of reassortment in human influenza viruses [PDF]

open access: yesProceedings of the National Academy of Sciences, 2020
Reassortment is an important source of genetic diversity in seg-mented viruses and is the main source of novel pathogenic influenza viruses. Despite this, studying the reassortment process has been constrained by the lack of a coherent, model-based infer-
Dudas, Gytis,   +4 more
core   +5 more sources

TreeKnit: Inferring ancestral reassortment graphs of influenza viruses. [PDF]

open access: yesPLoS Computational Biology, 2022
When two influenza viruses co-infect the same cell, they can exchange genome segments in a process known as reassortment. Reassortment is an important source of genetic diversity and is known to have been involved in the emergence of most pandemic ...
Pierre Barrat-Charlaix   +2 more
doaj   +2 more sources

Genome-Wide Reassortment Analysis of Influenza A H7N9 Viruses Circulating in China during 2013–2019

open access: yesViruses, 2022
Reassortment with the H9N2 virus gave rise to the zoonotic H7N9 avian influenza virus (AIV), which caused more than five outbreak waves in humans, with high mortality.
Dongchang He   +14 more
doaj   +2 more sources

Analyses and Insights into Genetic Reassortment and Natural Selection as Key Drivers of Piscine orthoreovirus Evolution

open access: yesViruses
Piscine orthoreovirus (PRV) is a pathogen that causes heart and skeletal muscle inflammation in Salmo salar and has also been linked to circulatory disorders in other farmed salmonids, such as Oncorhynchus kisutch and Oncorhynchus mykiss. The virus has a
Laura Solarte-Murillo   +5 more
doaj   +2 more sources

Evidence of Vaccine-related Reassortment of Rotavirus, Brazil, 2008–2010

open access: yesEmerging Infectious Diseases, 2013
Analysis of 27 rotavirus strains from vaccinated and unvaccinated children revealed reassortment events in 3 strains: a gene derived from a vaccine; a gene acquired from a circulating strain; and reassortment between circulating strains.
Tatiana Lundgren Rose   +6 more
doaj   +2 more sources

Potential for La Crosse virus segment reassortment in nature [PDF]

open access: yesVirology Journal, 2008
The evolutionary success of La Crosse virus (LACV, family Bunyaviridae) is due to its ability to adapt to changing conditions through intramolecular genetic changes and segment reassortment.
Geske Dave   +5 more
doaj   +2 more sources

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