Results 11 to 20 of about 16,546 (197)

New approaches for unravelling reassortment pathways [PDF]

open access: yesBMC Evolutionary Biology, 2013
Background Every year the human population encounters epidemic outbreaks of influenza, and history reveals recurring pandemics that have had devastating consequences.
Svinti Victoria   +2 more
doaj   +6 more sources

Predicting Hotspots for Influenza Virus Reassortment [PDF]

open access: yesEmerging Infectious Diseases, 2013
The 1957 and 1968 influenza pandemics, each of which killed ≈1 million persons, arose through reassortment events. Influenza virus in humans and domestic animals could reassort and cause another pandemic.
Trevon L. Fuller   +9 more
doaj   +6 more sources

Bayesian inference of reassortment networks reveals fitness benefits of reassortment in human influenza viruses [PDF]

open access: yesProceedings of the National Academy of Sciences, 2019
Significance Genetic recombination processes, such as reassortment, make it complex or impossible to use standard phylogenetic and phylodynamic methods. This is due to the fact that the shared evolutionary history of individuals has to be represented by a phylogenetic network instead of a tree.
Nicola F. Müller   +4 more
openaire   +5 more sources

HopPER: an adaptive model for probability estimation of influenza reassortment through host prediction

open access: yesBMC Medical Genomics, 2020
Background Influenza reassortment, a mechanism where influenza viruses exchange their RNA segments by co-infecting a single cell, has been implicated in several major pandemics since 19th century.
Rui Yin   +3 more
doaj   +2 more sources

In vivo reassortment of influenza viruses. [PDF]

open access: yesActa Biochimica Polonica, 2014
The genetic material of influenza A virus consists of eight negative-sense RNA segments. Under suitable conditions, the segmented structure of the viral genome allows an exchange of the individual gene segments between different strains, causing formation of new reassorted viruses.
Urbaniak, Kinga, Iwona Markowska-Daniel
openaire   +4 more sources

TreeKnit: Inferring ancestral reassortment graphs of influenza viruses. [PDF]

open access: yesPLoS Computational Biology, 2022
When two influenza viruses co-infect the same cell, they can exchange genome segments in a process known as reassortment. Reassortment is an important source of genetic diversity and is known to have been involved in the emergence of most pandemic ...
Pierre Barrat-Charlaix   +2 more
doaj   +2 more sources

Reassortment Patterns in Swine Influenza Viruses [PDF]

open access: yesPLoS Currents, 2009
Previous human influenza pandemics were the results of emerging viruses from non-human reservoirs, with at least two caused by strains of mixed human and avian origin. Also, many cases of swine influenza viruses have reportedly infected humans, including the recent human H1N1 strain, isolated in Mexico and the United States.
Hossein Khiabanian   +2 more
openaire   +7 more sources

Analyses and Insights into Genetic Reassortment and Natural Selection as Key Drivers of Piscine orthoreovirus Evolution

open access: yesViruses
Piscine orthoreovirus (PRV) is a pathogen that causes heart and skeletal muscle inflammation in Salmo salar and has also been linked to circulatory disorders in other farmed salmonids, such as Oncorhynchus kisutch and Oncorhynchus mykiss. The virus has a
Laura Solarte-Murillo   +5 more
doaj   +2 more sources

Probing orthobunyavirus reassortment using Bunyamwera and Batai viruses as models.

open access: yesPLoS Neglected Tropical Diseases
Reassortment is a critical evolutionary mechanism for segmented viruses, enabling the exchange of intact genome segments during co-infection and driving orthobunyavirus evolution; however, the molecular mechanisms underpinning this process remain unclear.
James M Bowen   +7 more
doaj   +2 more sources

Evidence of Vaccine-related Reassortment of Rotavirus, Brazil, 2008–2010

open access: yesEmerging Infectious Diseases, 2013
Analysis of 27 rotavirus strains from vaccinated and unvaccinated children revealed reassortment events in 3 strains: a gene derived from a vaccine; a gene acquired from a circulating strain; and reassortment between circulating strains.
Tatiana Lundgren Rose   +6 more
doaj   +2 more sources

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