Results 81 to 90 of about 103,970 (298)
The role of lipid metabolism in neuronal senescence
FEBS Open Bio, EarlyView.Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source
Employment During the 2001–2003 Recovery [PDF]
, 2005 This background paper examines job growth following the 2001 recession. After declining by about 1.6 million jobs during that recession, employment fell by more than an additional million jobs in the first 18 months following the end of the recession ...
U.S. Congressional Budget Office
core +1 more source
Body mass index rebound, weight gain in puberty, and risk of cardiovascular disease [PDF]
The Journal of Pediatrics, 2020 Osamu, Arisaka +3 more
openaire +2 more sources
HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
FEBS Open Bio, EarlyView.Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Лëд и снег, 2015 Residual strength and diameters of lichen Rhizocarpon sp. were measured on different elements of the Late Holocene glacial-cryogenic morphosculpture of frontal parts of glaciers № 29 and 31 in the Suntar-Khayat Range. All in all, 180 lichenometric sites (
A. A. Galanin +2 more
doaj +1 more source
The McCance Brain Care Score and Mortality: Evidence From a Large‐Scale Population‐Based Cohort
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives This study aimed to examine the relationship between the McCance Brain Care Score (BCS) and mortality in the general population. Methods We conducted a prospective, population‐based cohort study using data from the UK Biobank. Participants with complete data enabling calculation of BCS and full mortality information were included ...
Zhiqiang Xu, Xiaoxiao Wang, Nan Li
wiley +1 more source
IMPROVEMENT OF COMPRESSIBLITY CHARCTERISTICSOF NATURAL ORGANIC SOILS
Journal of Engineering and Sustainable Development, 2018 The aim of this paper is to investigate the possible improvement of the compressibility characteristics (compression index, rebound index, i.e.,)of natural organic soil by using cement dust and fly ash. Natural organic soil with different percentages of
Adel Hamed Majeed +2 more
doaj
Yantu gongcheng xuebaon order to explain the lagging settlement in the surrounding ground induced by pre-dewatering of excavations, one-dimensional consolidation creep tests are conducted on typical silty sand and silty soil at a metro station site of Jiangsu Province.
ZHU Jun 1, CHEN Shaobo 2, YING Xu 2, ZHOU You 2, ZHANG Siyu 3
doaj +1 more source