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Molecular Oncology, Volume 19, Issue S1, Page 1-940, June 2025.Abstracts submitted to the ‘EACR 2025 Congress: Innovative Cancer Science’, from 16–19 June 2025 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley +1 more source
Assembly of RecA-like Recombinases: Distinct Roles for Mediator Proteins in Mitosis and Meiosis [PDF]
, 2001 Members of the RecA family of recombinases from bacteriophage T4, Escherichia coli, yeast, and higher eukaryotes function in recombination as higher-order oligomers assembled on tracts of single-strand DNA (ssDNA).
Gasior, Stephen L
core +3 more sources
Epidermal γδ T cells sense precancerous cellular dysregulation and initiate immune responses [PDF]
, 2017 Hyperplasia associated with a loss of tissue homeostasis can induce DNA replication stress, leading to precancerous dysregulation. Epidermal γδ T cells reside in the primary barrier that protects against diverse environmental insults; however, the ...
Chambon, Pierre +7 more
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Engineering Cre Recombinase for Genome Engineering [PDF]
, 2016 Cre recombinase recombines its DNA target, loxP sites, without help of accessory proteins or DNA repair systems. The simplicity of Cre-lox system has been widely utilized for genome editing, especially in mouse genetics.
Zhang, Chi
core +1 more source
Precise excision of HTLV-1 provirus with a designer-recombinase. [PDF]
Mol Ther, 2023 Rojo-Romanos T +11 more
europepmc +1 more source
Correction of a Factor VIII genomic inversion with designer-recombinases [PDF]
Despite advances in nuclease-based genome editing technologies, correcting human disease-causing genomic inversions remains a challenge. Here, we describe the potential use of a recombinase-based system to correct the 140 kb inversion of the F8 gene ...
Buchholz, Frank +16 more
core +2 more sources
Determinants of selectivity in Xer site-specific recombination [PDF]
, 1996 Blakely, G, Sherratt, D
core +1 more source
, 2014 Genomic analysis of a large set of phages infecting the common hostMycobacterium smegmatis mc2155 shows that they span considerable genetic diversity.
Anders, Kirk R. +40 more
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