Results 131 to 140 of about 2,229 (161)
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Wistar rat dermis recellularization
Research in Veterinary Science, 2020Skin lesions are normal to all species, regardless of gender or age. The skin, the largest organ of the body, has function as a primary barrier to the chemical, physical and biological aggressions of the environment. In animals, these lesions may be due to fights and/or predations, also as in humans, there is a very common cause of dermal lesions that ...
Maria Angelica Miglino
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Strategies based on organ decellularization and recellularization [PDF]
Transplant International, 2019 Transplantation is the only curative treatment option available for patients suffering from end-stage organ failure, improving their quality of life and long-term survival. However, because of organ scarcity, only a small number of these patients actually benefit from transplantation.
Karl H Hillebrandt +2 more
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Histological structure affects recellularization of decellularized arteries
Materials Science and Engineering C, 2017Decellularized arteries were prepared to evaluate the in vivo recellularization of biological material after implantation. Porcine aortas and radial arteries were decellularized using high-hydrostatic pressure to form materials with histologically-different structures.
Jun Negishi +2 more
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Numerical assessment of recellularization conditions to vessel occlusion
Biomechanics and Modeling in Mechanobiology, 2023To ensure the functional properties of an organ generated by the process of decellularization and recellularization, the initial density and distribution of seeding cells in the parenchymal space should be maximized. However, achieving a uniform distribution of cells across the entire organ is not straightforward because of vessel occlusion. This study
Van, Lap Nguyen, Hiromichi, Obara
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Limitations of recellularized biological scaffolds for human transplantation
Journal of Tissue Engineering and Regenerative Medicine, 2020A shortage of donor organs for transplantation and the dependence of the recipients on immunosuppressive therapy have motivated researchers to consider alternative regenerative approaches. The answer may reside in acellular scaffolds generated from cadaveric human and animal tissues.
Claudia Bilodeau +3 more
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Current Opinion in Organ Transplantation, 2014
Allogeneic organ transplantation is burdened by donor shortage, graft rejection and adverse effects of lifelong immune suppression. Engineering bioartificial organs from acellular organ scaffolds and patient-derived cells are a new approach to potentially overcome these limitations.Decellularized organs yield a scaffold of extracellular matrix on which
Philipp T, Moser, Harald C, Ott
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Allogeneic organ transplantation is burdened by donor shortage, graft rejection and adverse effects of lifelong immune suppression. Engineering bioartificial organs from acellular organ scaffolds and patient-derived cells are a new approach to potentially overcome these limitations.Decellularized organs yield a scaffold of extracellular matrix on which
Philipp T, Moser, Harald C, Ott
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Decellularization and Recellularization of Cartilage
2017Decellularization of cartilage enables the use of cartilage allografts or xenografts as natural scaffolds for repair and regeneration of injured cartilage. The preservation of the extracellular matrix ultrastructure of the graft makes this a promising tool for cartilage tissue engineering.
Catherine A, Bautista, Bahar, Bilgen
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Decellularizing and Recellularizing Adult Mouse Kidneys
2019Decellularization is the process by which resident cells are lysed and cellular debris is removed from the tissue, leaving behind the extracellular matrix scaffold. The extracellular matrix scaffold can be used for three-dimensional culturing of cells.
Theresa, Chow +2 more
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Evaluating different methods for kidney recellularization
2023End-stage renal disease (ESRD) is a condition where the kidneys fail to effectively filter waste and excess fluids from the blood. In Canada, the number of ESRD patients has increased by 24% over the past decade. While dialysis is a treatment option, kidney transplantation remains the gold standard due to higher survival rates.
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Characterization of CD133 Antibody-Directed Recellularized Heart Valves
Journal of Cardiovascular Translational Research, 2015CD133mAb conjugation (CD133-C) hastens in vivo recellularization of decellularized porcine heart valve scaffolds when placed in the pulmonary position of sheep. We now characterize this early cellularization process 4 h, 3, 7, 14, 30, or 90 days post-implantation.
J Koudy, Williams +5 more
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