Results 61 to 70 of about 4,532 (195)

A proposed model of xeno-keratoplasty using 3D printing and decellularization

Frontiers in Pharmacology, 2023
Corneal opacity is a leading cause of vision impairment and suffering worldwide. Transplantation can effectively restore vision and reduce chronic discomfort. However, there is a considerable shortage of viable corneal graft tissues.
Xinyu Wang, Xinyu Wang, Rawdah Taha Elbahrawi, Azhar Mohamud Abdukadir, Zehara Mohammed Ali, Vincent Chan, Peter R. Corridon, Peter R. Corridon, Peter R. Corridon, Peter R. Corridon   +9 more
doaj   +1 more source

The Cellular and Physiological Basis for Lung Repair and Regeneration: Past, Present, and Future. [PDF]

, 2020
The respiratory system, which includes the trachea, airways, and distal alveoli, is a complex multi-cellular organ that intimately links with the cardiovascular system to accomplish gas exchange.
Basil, Maria C, Chapman, Hal A, Engler, Anna E, Guo, Minzhe, Herriges, Michael J, Kathiriya, Jaymin J, Katzen, Jeremy, Kotton, Darrell N, Morrisey, Edward E, Rock, Jason R, Snoeck, Hans-Willem, Vunjak-Novakovic, Gordana, Whitsett, Jeffrey A, Windmueller, Rebecca, Ysasi, Alexandra B, Zacharias, William J   +15 more
core   +1 more source

Pushing the envelope in tissue engineering: Ex vivo production of thick vascularized cardiac extracellular matrix constructs [PDF]

, 2015
Functional vascularization is a prerequisite for cardiac tissue engineering of constructs with physiological thicknesses. We previously reported the successful preservation of main vascular conduits in isolated thick acellular porcine cardiac ventricular
Boey, Yin Chiang Freddy, Bronshtein, Tomer, Dahan, Nitsan, Gvirtz, Maskit, Machluf, Marcelle, Nguyen, Evelyne Bao-Vi, Oh, Steve K.W., Reuveny, Shaul, Sarig, Hadar, Sarig, Udi, Scheper, Thomas, Ting, Sherwin, Venkatraman, Subbu S., Wang, Yao   +13 more
core   +2 more sources

Organ Transplantation: Current Status, Challenges, and Future Prospects

MedComm, Volume 7, Issue 1, January 2026.
Organ transplantation success relies on precise modulation of the alloimmune response across distinct temporal phases of rejection. Hyperacute rejection results from preformed antibodies activating complement and causing thrombosis, while acute rejection involves T cell‐ and antibody‐mediated mechanisms that drive endothelial activation and ...
Xinqiang Li, Ruidong Ding, Jinzhen Cai
wiley   +1 more source

Bioengineering lungs: An overview of current methods, requirements, and challenges for constructing scaffolds

Frontiers in Bioengineering and Biotechnology, 2022
Chronic respiratory diseases remain a significant health burden worldwide. The only option for individuals with end-stage lung failure remains Lung Transplantation.
Shahad Shakir, Tillie Louise Hackett, Tillie Louise Hackett, Leila B. Mostaço-Guidolin   +3 more
doaj   +1 more source

Mesenchymal Stromal Cells to Regenerate Emphysema:On the Horizon? [PDF]

, 2018
Mesenchymal stem or stromal cells (MSCs) are multipotent cells that play a pivotal role in various phases of lung development and lung homeostasis, and potentially also lung regeneration.
Heijink, Irene H, Kruk, Dennis M L W, Slebos, Dirk-Jan, Ten Hacken, Nick H, Timens, Wim   +4 more
core   +1 more source

Next‐Generation Therapies for Gastrointestinal Repair: Converging Traditional Medicine and Tissue Engineering

JGH Open, Volume 9, Issue 12, December 2025.
ABSTRACT The gastrointestinal (GI) tract plays a vital role in regulating metabolic pathways, nutrient absorption, and cellular homeostasis. Abnormalities in the GI tract often arise from unhealthy lifestyles, genetic mutations, and prolonged medication use, leading to disorders such as ulcers, cirrhosis, and malignancies.
Archna Dhasmana, Indra Rautela, Atul Singh, Ayushi Santhanam, Sumira Malik, R. K. Govindarajan, Subham Preetam   +6 more
wiley   +1 more source

Tissue specificity of decellularized rhesus monkey kidney and lung scaffolds. [PDF]

PLoS ONE, 2013
Initial steps in establishing an optimal strategy for functional bioengineered tissues is generation of three-dimensional constructs containing cells with the appropriate organization and phenotype.
Karina H Nakayama, C Chang I Lee, Cynthia A Batchelder, Alice F Tarantal   +3 more
doaj   +1 more source

Modified nanofat grafting: Stromal vascular fraction simple and efficient mechanical isolation technique and perspectives in clinical recellularization applications

Frontiers in Bioengineering and Biotechnology, 2022
Background: Nanofat grafting (NG) is a simple and cost-effective method of lipoaspirates with inter-syringe passages, to produce stromal vascular fraction (SVF) and isolate adipose-derived stem cells (ASCs).
Paul Girard, Paul Girard, Paul Girard, Joelle Dulong, Joelle Dulong, Jerome Duisit, Camille Mocquard, Camille Mocquard, Camille Mocquard, Simon Le Gallou, Simon Le Gallou, Benoit Chaput, Benoit Chaput, Elise Lupon, Eric Watier, Audrey Varin, Karin Tarte, Karin Tarte, Nicolas Bertheuil, Nicolas Bertheuil, Nicolas Bertheuil   +20 more
doaj   +1 more source

Generation of Lung Epithelium from Pluripotent Stem Cells [PDF]

, 2013
The understanding of key processes and signaling mechanisms in lung development has been mainly demonstrated through gain and loss of function studies in mice, while human lung development remains largely unexplored due to inaccessibility. Several recent
Amy P. Wong, Janet Rossant
core   +1 more source