Results 51 to 60 of about 2,229 (161)
Artificial Organs, EarlyView.The use of autologous connective tissue, such as pericardium or peritoneum, combined with controlled tissue treatment, has the potential to result in a more durable heart valve prosthesis than current commercial prostheses. ABSTRACT Introduction Valvular heart disease remains a leading cause of morbidity and mortality. Current biological and mechanical
Marvin Steitz +17 more
wiley +1 more source
BMEMat, Volume 4, Issue 2, June 2026.A novel nanoenzyme based on cerium ions‐tannic acid metal‐polyphenol framework (FCT) has been developed and loaded onto DHVs for targeting M1 macrophages to reduce their ROS level and reprogram macrophage phenotype, thereby eliminating inflammation, promoting endothelialization and adaptive matrix remodeling of scaffolds, offering a promising strategy ...
Peng Song +9 more
wiley +1 more source
Decellularized scaffold of cryopreserved rat kidney retains its recellularization potential. [PDF]
PLoS ONE, 2017 The multi-cellular nature of renal tissue makes it the most challenging organ for regeneration. Therefore, till date whole organ transplantations remain the definitive treatment for the end stage renal disease (ESRD). The shortage of available organs for
Baldeep Chani +4 more
doaj +1 more source
Exploration, Volume 6, Issue 3, June 2026.This graphic abstract depicts the convergence of artificial intelligence, genetic technologies, bioengineering, and rehabilitation as the core pillars of next‐generation surgery. These domains collectively enhance preoperative planning, intraoperative precision, tissue reconstruction, and postoperative recovery, driving a paradigm shift toward ...
Dengxiong Li +17 more
wiley +1 more source
De- and recellularization of the pig uterus: a bioengineering pilot study [PDF]
Biology of Reproduction, 2016 Absolute uterine factor infertility, or the absence of a functional uterus, has a prevalence of 3%-5% in the general population. Despite the great strides being made in reproductive medicine, patients diagnosed with absolute uterine factor infertility remain untreatable.
Campo H +5 more
openaire +3 more sources
PLoS ONE, 2021 Autologous vascular grafts are widely used in revascularization surgeries for small caliber targets. However, the availability of autologous conduits might be limited due to prior surgeries or the quality of vessels.
Shunji Kurokawa +9 more
doaj +1 more source
Advanced Healthcare Materials, Volume 15, Issue 8, 23 February 2026.Decellularized liver extracellular matrix scaffolds provide a platform to study dormant liver‐metastatic colorectal cancer. They induce reversible dormancy, in combination with nutrient depletion and low dose chemotherapy, through cell cycle arrest and chemotherapy resistance.
Sabrina N. VandenHeuvel +13 more
wiley +1 more source
Recellularization of a novel off-the-shelf valve following xenogenic implantation into the right ventricular outflow tract. [PDF]
PLoS ONE, 2017 Current research on valvular heart repair has focused on tissue-engineered heart valves (TEHV) because of its potential to grow similarly to native heart valves.
Ryan S Hennessy +12 more
doaj +1 more source
Innovative Biotechnology for Generation of Cardiac Tissue
Applied Sciences, 2021 Heart transplantation remains the only curative treatment for end-stage heart failure. This life-saving option continues to be limited by the low number of organ donors, graft rejection and adverse effects of immunosuppressants. Engineering bioartificial
Greta Ionela Barbulescu +8 more
doaj +1 more source
Advanced Materials, Volume 38, Issue 8, 6 February 2026.This study presents human in vitro rheumatoid arthritis models using chondrocytes recellularized type II collagen scaffold and 3D‐bioprinted Gelatin‐Matrigel hydrogels with fibroblast‐like synoviocytes, pro‐inflammatory macrophages, and protective barrier macrophages, closely recapitulating key rheumatoid arthritis pathological features.
Huiqun Zhou +6 more
wiley +1 more source