Results 71 to 80 of about 2,229 (161)
VIEW, Volume 6, Issue 6, December 2025.Angiogenesis is an essential process in tissue regeneration, as it prevents complications such as necrosis, inflammation, and fibrosis. mADM decellularized by the supercritical carbon dioxide method exhibits high preservation of the extracellular matrix and various growth factors.
Hyo‐Jin Kim +14 more
wiley +1 more source
Journal of Biomedical Materials Research Part B: Applied Biomaterials, Volume 113, Issue 11, November 2025.ABSTRACT Valvular heart disease (VHD) represents a significant global health challenge, affecting over 2.5% of the population and disproportionately impacting older adults due to age‐related degenerative processes. Current treatment options—mechanical and bioprosthetic valves—both present substantial limitations that impact patient quality of life and ...
Nikolaos P. Tzavellas +8 more
wiley +1 more source
Preparation of Decellularized Liver Scaffolds and Recellularized Liver Grafts [PDF]
, 2017 Severe liver disease is the 12th leading cause of death in the USA, with organ transplantation often being the only viable option for treatment. However, due to the shortage of viable donor livers, it is estimated that over 1200 patients died in 2015 while waiting for liver transplantation.
Yibin, Chen +3 more
openaire +2 more sources
A New Method for Preparation of Decellularized Human Scaffolds for Facial Reconstruction
Current Issues in Molecular BiologyVascularized composite allotransplantation (VCA) has emerged as a robust alternative for addressing anatomically complex defects but requires a toxic lifelong immunosuppressive regimen. Tissue engineering offers the promise of creating recipient-specific
Elise Lupon +9 more
doaj +1 more source
Biomimetic Cell Membrane‐Coated Scaffolds for Enhanced Tissue Regeneration
Advanced Materials, Volume 37, Issue 40, October 9, 2025.This review examines the development and use of cell membrane‐coated scaffolds in tissue engineering. Bioinspired phospholipid and glycocalyx coatings enhance anti‐fouling, anti‐thrombogenic, and selective molecular recognition properties. Native cell membrane coatings further support cell‐specific interactions, immune modulation, and reduced bacterial
Carmen Alvarez‐Lorenzo +5 more
wiley +1 more source
Journal of Biomedical Materials Research Part A, Volume 113, Issue 10, October 2025.ABSTRACT Hybrid materials are gaining increasing attention for several applications since they properly combine biological and synthetic components, leveraging the advantages of both; thus, these materials can integrate with the host organism to support proper functions, offering new promising solutions, especially in the biomedical field.
Martina Todesco +13 more
wiley +1 more source
Recellularized Native Kidney Scaffolds as a Novel Tool in Nephrotoxicity Screening [PDF]
Drug Metabolism and Disposition, 2018 Drug-induced kidney injury in medicinal compound development accounts for over 20% of clinical trial failures and involves damage to different nephron segments, mostly the proximal tubule. Yet, currently applied cell models fail to reliably predict nephrotoxicity; neither are such models easy to establish.
Michele Fedecostante +8 more
openaire +7 more sources
Journal of Biomedical Materials Research Part A, Volume 113, Issue 10, October 2025.ABSTRACT Rupture of the anterior cruciate ligament (ACL) is a common injury resulting in joint instability. Tendon autografts, the gold standard to reconstruct a ruptured ACL, contain dead or dying cells upon implantation that can initiate early localized catabolic and inflammatory events.
Janne Spierings +6 more
wiley +1 more source
Optimizing Recellularization of Whole Decellularized Heart Extracellular Matrix
PLoS ONE, 2014 Perfusion decellularization of cadaveric hearts removes cells and generates a cell-free extracellular matrix scaffold containing acellular vascular conduits, which are theoretically sufficient to perfuse and support tissue-engineered heart constructs.
Matthew J Robertson +4 more
openaire +4 more sources
Lung bioengineering: advances and challenges in lung decellularization and recellularization
Current Opinion in Organ Transplantation, 2018 Purpose of review Bioengineering the lung based on its natural extracellular matrix (ECM) offers novel opportunities to overcome the shortage of donors, to reduce chronic allograft rejections, and to improve the median survival rate of transplanted patients.
Juan J, Uriarte +4 more
openaire +3 more sources