Results 31 to 40 of about 2,229 (161)

Decellularized Periodontal Ligament Cell Sheets with Recellularization Potential [PDF]

Journal of Dental Research, 2014
The periodontal ligament is the key tissue facilitating periodontal regeneration. This study aimed to fabricate decellularized human periodontal ligament cell sheets for subsequent periodontal tissue engineering applications. The decellularization protocol involved the transfer of intact human periodontal ligament cell sheets onto ...
Farag, A., Vaquette, C., Theodoropoulos, C., Hamlet, S. M., Hutmacher, D. W., Ivanovski, S.   +5 more
openaire   +5 more sources

Recellularization of decellularized porcine caval veins

Biomedical Science and Engineering, 2021
Decellularized material has been reported to be more suitable for cells to grow when compared to synthetic materials because repopulating cells are provided with the structural environment of native tissue. The aim of this study is to prepare and to test porcine caval veins through their decellularization followed by repopulation with human endothelial
Maria Stefania Massaro, Richard Pálek, Jáchym Rosendorf, Anna Malečková, Lenka Červenková, Roshan K. Singh, Robert Polák, Václav Liška, Vladimíra Moulisová   +8 more
openaire   +2 more sources

Evaluating different methods for kidney recellularization. [PDF]

Sci Rep
Abstract This study explores a potential solution to the shortage of kidneys for transplantation in end-stage renal disease (ESRD). Currently, kidney transplantation is the best option, but there aren't enough organs available. The researchers used tissue engineering to evaluate the possibility for creating kidneys for transplantation.
Luque-Badillo AC, Monjaras-Avila CU, Adomat H, So A, Chavez-Muñoz C.   +4 more
europepmc   +4 more sources

Easy-to-Assembly System for Decellularization and Recellularization of Liver Grafts in a Bioreactor

Micromachines, 2023
Decellularization of organs creates an acellular scaffold, ideal for being repopulated by cells. In this work, a low-cost perfusion system was created to be used in the process of liver decellularization and as a bioreactor after recellularization.
Maurício Felisberto Borges, Natasha Maurmann, Patricia Pranke   +2 more
doaj   +1 more source

Uterus bioengineering as a future alternative to uterus transplantation

Clinical and Experimental Obstetrics & Gynecology, 2022
Objective: To review the current knowledge on uterus bioengineering and discuss potential future directives. Uterus bioengineering may solve two major hurdles in organ transplantation of a uterus, organ shortage and control of rejection by ...
Arvind Manikantan Padma, Mats Brännström, Mats Hellström   +2 more
doaj   +1 more source

A Two-Step Bioreactor for Lung Recellularization [PDF]

, 2020
Abstract Bioreactors for reseeding of decellularized lung scaffolds have evolved with a wide variety of advancements. These include biomimetic mechanical stimulation, constant nutrient flow, multi-output monitoring, and large mammal scaling.
Bethany Young, Leigh-Ann M. Antczak, Keerthana Shankar, Rebecca L. Heise   +3 more
openaire   +1 more source

Whole Liver Derived Acellular Extracellular Matrix for Bioengineering of Liver Constructs: An Updated Review

Bioengineering, 2023
Biomaterial templates play a critical role in establishing and bioinstructing three-dimensional cellular growth, proliferation and spatial morphogenetic processes that culminate in the development of physiologically relevant in vitro liver models ...
Tanveer Ahmed Mir, Alaa Alzhrani, Makoto Nakamura, Shintaroh Iwanaga, Shadil Ibrahim Wani, Abdullah Altuhami, Shadab Kazmi, Kenchi Arai, Talal Shamma, Dalia A. Obeid, Abdullah M. Assiri, Dieter C. Broering   +11 more
doaj   +1 more source

Lung Microvascular Niche, Repair, and Engineering

Frontiers in Bioengineering and Biotechnology, 2020
Biomaterials have been used for a long time in the field of medicine. Since the success of “tissue engineering” pioneered by Langer and Vacanti in 1993, tissue engineering studies have advanced from simple tissue generation to whole organ generation with
Tomoshi Tsuchiya, Tomoshi Tsuchiya, Ryoichiro Doi, Tomohiro Obata, Go Hatachi, Takeshi Nagayasu   +5 more
doaj   +1 more source

Systematic in vitro comparison of decellularization protocols for blood vessels.

PLoS ONE, 2018
Decellularization of native blood vessels is a promising technology to generate 3D biological scaffolds for vascular grafting. Blood vessel decellularization has been performed in previous studies under various experimental conditions, that complicates ...
Robin Simsa, Arvind Manikantan Padma, Philipp Heher, Mats Hellström, Andreas Teuschl, Lachmi Jenndahl, Niklas Bergh, Per Fogelstrand   +7 more
doaj   +1 more source

A REVIEW OF CELLULARIZATION STRATEGIES FOR TISSUE ENGINEERING OF WHOLE ORGANS

Frontiers in Bioengineering and Biotechnology, 2015
With the advent of whole organ decellularization, extracellular matrix scaffolds suitable for organ engineering were generated from numerous tissues, including the heart, lung, liver, kidney and pancreas, for use as alternatives to traditional organ ...
Michelle E Scarritt, Nicholas C Pashos, Bruce Alan Bunnell   +2 more
doaj   +1 more source