Results 21 to 30 of about 2,229 (161)

Decellularized blood vessel development: Current state-of-the-art and future directions

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
Vascular diseases contribute to intensive and irreversible damage, and current treatments include medications, rehabilitation, and surgical interventions.
Xinyu Wang   +4 more
doaj   +1 more source

Liver Tissue Bioengineering: Decellularization and Recellularization. Histological and Immunohistochemical Study [PDF]

open access: yesThe Egyptian Journal of Histology, 2023
Introduction: The need for liver transplantation is rising due to increase in end-stage liver diseases. Testing drug toxicity on either liver tissue or on adult hepatocytes is crucial as it is the major drug metabolizing organ.Aim of the Work: This study
Shaimaa Khedr   +2 more
doaj   +1 more source

Towards a bioengineered uterus: bioactive sheep uterus scaffolds are effectively recellularized by enzymatic preconditioning

open access: yesnpj Regenerative Medicine, 2021
Uterine factor infertility was considered incurable until recently when we reported the first successful live birth after uterus transplantation.
Arvind Manikantan Padma   +9 more
doaj   +1 more source

Asthmatic Bronchial Matrices Determine the Gene Expression and Behavior of Smooth Muscle Cells in a 3D Culture Model

open access: yesFrontiers in Allergy, 2021
Asthma is associated with increased deposition and altered phenotype of airway smooth muscle (ASM) cells. However, little is known about the processes responsible for these changes. It has been suggested that alterations of the extracellular matrix (ECM)
Selma Ben Hamouda   +4 more
doaj   +1 more source

Decellularization and Recellularization Methodology for Human Saphenous Veins [PDF]

open access: yesJournal of Visualized Experiments, 2018
Vascular conduits used during most vascular surgeries are allogeneic or synthetic grafts that often lead to complications caused by immunosuppression and poor patency. Tissue engineering offers a novel solution to generate personalized grafts with a natural extracellular matrix containing the recipient's cells using the method of decellularization and ...
Kumar Kuna, Vijay   +2 more
openaire   +2 more sources

The Recellularized Liver Matrix: A Novel Way of Transplantation? [PDF]

open access: yesHepatology, 2010
Abstract Orthotopic liver transplantation is the only available treatment for severe liver failure, but it is currently limited by organ shortage.
Christer, Baeck, Konrad, Streetz
openaire   +2 more sources

Recent Advances in Liver Engineering With Decellularized Scaffold

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
Liver transplantation is currently the only effective treatment for patients with end-stage liver disease; however, donor liver scarcity is a notable concern. As a result, extensive endeavors have been made to diversify the source of donor livers.
Qingqing Dai   +6 more
doaj   +1 more source

Sustained in vivo perfusion of a re-endothelialized tissue engineered kidney graft in a human-scale animal model

open access: yesFrontiers in Bioengineering and Biotechnology, 2023
Introduction: Despite progress in whole-organ decellularization and recellularization, maintaining long-term perfusion in vivo remains a hurdle to realizing clinical translation of bioengineered kidney grafts. The objectives for the present study were to
Joseph S. Uzarski   +10 more
doaj   +1 more source

Experimental Evaluation of Kidney Regeneration by Organ Scaffold Recellularization [PDF]

open access: yesScientific Reports, 2017
AbstractThe rising number of patients needing renal replacement therapy, alongside the significant clinical and economic limitations of current therapies, creates an imperative need for new strategies to treat kidney diseases. Kidney bioengineering through the production of acellular scaffolds and recellularization with stem cells is one potential ...
Remuzzi, Andrea   +7 more
openaire   +3 more sources

EXPERIENCE OF PERFUSION RECELLULARIZATION OF BIOLOGICAL LUNG SCAFFOLD IN RATS

open access: yesВестник трансплантологии и искусственных органов, 2016
Aim. The main aim of our research is to evaluate the process of rat lung decellularization and recellularization as the initial step of tissue-engineered organs creation.Materials and methods.
E. V. Kuevda   +8 more
doaj   +1 more source

Home - About - Disclaimer - Privacy