Decellularization and Recellularization Technologies in Tissue Engineering
Cell Transplantation, 2014 Decellularization is the process by which cells are discharged from tissues/organs, but all of the essential cues for cell preservation and homeostasis are retained in a three-dimensional structure of the organ and its extracellular matrix components ...
Ru-Huei Fu +2 more
exaly +4 more sources
Application of decellularization-recellularization technique in plastic and reconstructive surgery
Chinese Medical Journal, 2023 . In the field of plastic and reconstructive surgery, the loss of organs or tissues caused by diseases or injuries has resulted in challenges, such as donor shortage and immunosuppression.
Yujia Shang +8 more
doaj +3 more sources
Development of a 3D tumor model based on decellularized matrix using high-throughput approaches [PDF]
Frontiers in Bioengineering and BiotechnologyPrecision medicine aims to develop 3D tumor models to validate new therapies and investigate disease mechanisms by isolating the extracellular matrix as a foundation for recreating tumors in vitro.
Homayoon Siahmansouri +6 more
doaj +2 more sources
A Review on Bioengineering the Bovine Mammary Gland: The Role of the Extracellular Matrix and Reconstruction Prospects [PDF]
BioengineeringThe mammary gland is a modified sweat gland responsible for milk production. It is affected by diseases that reduce animals’ quality of life, consequently leading to economic losses in livestock.
Fernando Chissico Júnior +6 more
doaj +2 more sources
Decellularization techniques: unveiling the blueprint for tracheal tissue engineering [PDF]
Frontiers in Bioengineering and BiotechnologyCertain congenital or acquired diseases and defects such as tracheo-oesophageal fistula, tracheomalacia, tracheal stenosis, airway ischemia, infections, and tumours can cause damage to the trachea.
Keisha T. Gomes +9 more
doaj +2 more sources
Decellularized porcine vascular grafts: structural integrity and translational potential for allogeneic implantation [PDF]
Frontiers in Bioengineering and BiotechnologyDecellularized vascular grafts (DVGs) are a promising alternative to synthetic prostheses for applications requiring long-term patency and biological integration.
Liqi Zhao +9 more
doaj +2 more sources
Recellularization of Decellularized Venous Grafts Using Peripheral Blood: A Critical Evaluation
EBioMedicine, 2018 Vascular disease is a major cause of death worldwide, and the growing need for replacement vessels is not fully met by autologous grafts or completely synthetic alternatives.
Jonny Hisdal +2 more
exaly +3 more sources
Bioengineering of vascularized porcine flaps using perfusion-recellularization
Scientific ReportsLarge volume soft tissue defects greatly impact patient quality of life and function while suitable repair options remain a challenge in reconstructive surgery.
Michael S. Xu +6 more
doaj +3 more sources
Transforming meat waste into sustainable corneal keratoplasty models [PDF]
Frontiers in Bioengineering and BiotechnologyWith a rapidly global population, there is a critical need to enhance food production and waste management. This necessity is driving opportunities for sustainable integrated food chains committed to biovalorization and circular bioeconomic practices ...
Ayman Mobin +5 more
doaj +2 more sources
Decellularization and Recellularization of Whole Livers [PDF]
Journal of Visualized Experiments, 2011 The liver is a complex organ which requires constant perfusion for delivery of nutrients and oxygen and removal of waste in order to survive. Efforts to recreate or mimic the liver microstructure with grounds up approach using tissue engineering and microfabrication techniques have not been successful so far due to this design challenge.
Basak E, Uygun +6 more
openaire +2 more sources