Results 81 to 90 of about 2,128 (154)

Advances in CRISPR‐Cas9 in lineage tracing of model animals

Animal Models and Experimental Medicine, Volume 8, Issue 6, Page 1004-1022, June 2025.
Cell lineage tracing is a key technology for describing the developmental history of individual progenitor cells and assembling them to form a lineage development tree. However, traditional methods have limitations of poor stability and insufficient resolution.
Jingchao Cao, Zihang Guo, Xueling Xu, Pan Li, Yi Fang, Shoulong Deng   +5 more
wiley   +1 more source

Recellularization of Decellularized Venous Grafts Using Peripheral Blood: A Critical Evaluation

EBioMedicine, 2018
Vascular disease is a major cause of death worldwide, and the growing need for replacement vessels is not fully met by autologous grafts or completely synthetic alternatives.
Mia H. Rambøl, Jonny Hisdal, Jon O. Sundhagen, Jan E. Brinchmann, Antonio Rosales   +4 more
doaj   +1 more source

From Cartilage to Matrix: Protocols for the Decellularization of Porcine Auricular Cartilage

Bioengineering
The shortage of tissues and damaged organs led to the development of tissue engineering. Biological scaffolds, created from the extracellular matrix (ECM) of organs and tissues, have emerged as a promising solution for transplants.
Ana Caroline dos Santos, Livia Maria Barbosa de Andrade, Raí André Querino Candelária, Juliana Casanovas de Carvalho, Maria Carolina Miglino Valbão, Rodrigo da Silva Nunes Barreto, Marcelo Domingues de Faria, Rogerio Leone Buchaim, Daniela Vieira Buchaim, Maria Angelica Miglino   +9 more
doaj   +1 more source

Hepatocytes isolation from adult rats for liver recellularization

The Moldovan Medical Journal, 2019
Background: Currently hepatocytes obtaining is prerequisite to create the necessary conditions for medical research, because it is an important tool in developing of new strategies in tissue engineering domain, which represents obtaining functional organs in laboratory conditions.
Jian, Mariana, Cobzac, Vitalie, Vartic, Victoria, Nacu, Viorel   +3 more
openaire   +4 more sources

Reconstruction of the human nipple–areolar complex: a tissue engineering approach

Frontiers in Bioengineering and Biotechnology
Introduction: Nipple–areolar complex (NAC) reconstruction after breast cancer surgery is challenging and does not always provide optimal long-term esthetic results.
Louis Maistriaux, Louis Maistriaux, Vincent Foulon, Lies Fievé, Daela Xhema, Robin Evrard, Julie Manon, Maude Coyette, Maude Coyette, Caroline Bouzin, Yves Poumay, Pierre Gianello, Catherine Behets, Benoît Lengelé, Benoît Lengelé   +14 more
doaj   +1 more source

Decellularized Tendon Extracellular Matrix—A Valuable Approach for Tendon Reconstruction?

Cells, 2012
Tendon healing is generally a time-consuming process and often leads to a functionally altered reparative tissue. Using degradable scaffolds for tendon reconstruction still remains a compromise in view of the required high mechanical strength of tendons.
Anke Lohan, Wolfgang Ertel, Onays Al-Sadi, Gundula Schulze-Tanzil   +3 more
doaj   +1 more source

Optimized Decellularization of a Porcine Fasciocutaneaous Flap

Bioengineering
Reconstructive techniques to repair severe tissue defects include the use of autologous fasciocutaneous flaps, which may be limited due to donor site availability or lead to complications such as donor site morbidity.
Elise Lupon, Aylin Acun, Corentin B. Taveau, Ruben Oganesyan, Hyshem H. Lancia, Alec R. Andrews, Mark A. Randolph, Curtis L. Cetrulo, Alexandre G. Lellouch, Basak E. Uygun   +9 more
doaj   +1 more source

63 Allogeneic Recellularized Lung Orthotopic (ARLO) Transplant Research

Journal of Clinical and Translational Science
OBJECTIVES/GOALS: As of 2021, the lung transplantation waiting list has a mortality rate of 7.6 deaths per 100 patient-years. Bioengineered human organs is an emerging field of tissue engineering with a goal of developing suitable organs for transplantation.
Douglas Tran, Douglas Tran, Bartley Griffith, Zhongjun Wu   +3 more
openaire   +2 more sources

Three-dimensional reconstruction of a biliary system in a bioengineered liver using decellularized scaffold. [PDF]

Sci Rep
Horie H, Fukumitsu K, Hanabata Y, Karasuyama T, Iwaki K, Munekage F, Makino K, Ito T, Tomofuji K, Kojima H, Ogiso S, Uebayashi EY, Uematsu H, Coppo R, Onuma K, Inoue M, Ishii T, Hatano E.   +17 more
europepmc   +1 more source

Anti-CD31 antibody preconditioning for enhancement of endothelial cell capture and vascularization: a novel strategy for bioengineering lung scaffolds. [PDF]

J Biol Eng
Kamata S, Zargar A, Taniguchi D, Suzuki Y, Lo A, Bian S, Chen E, Ligi S, Keshavjee S, Okada Y, Haykal S, Bazylak A, Waddell TK, Karoubi G.   +13 more
europepmc   +1 more source