BED estimates of HIV incidence: resolving the differences, making things simpler. [PDF]
PLoS ONE, 2012 Develop a simple method for optimal estimation of HIV incidence using the BED capture enzyme immunoassay.Use existing BED data to estimate mean recency duration, false recency rates and HIV incidence with reference to a fixed time period, T.Compare BED ...
John Hargrove +2 more
doaj +1 more source
Centering, Anaphora Resolution, and Discourse Structure [PDF]
, 1997 Centering was formulated as a model of the relationship between attentional state, the form of referring expressions, and the coherence of an utterance within a discourse segment (Grosz, Joshi and Weinstein, 1986; Grosz, Joshi and Weinstein, 1995).
Walker, Marilyn A.
core +2 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Data quality in telephone surveys and the effect of questionnaire length: a cross-national experiment [PDF]
, 2010 Respondents in long telephone survey interviews may adopt satisficing strategies as they approach the end of the questionnaire (Holbrook, Green and Krosnick, 2003).
Allum, Nick +3 more
core +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Timeliness of information: A basic model [PDF]
information;models;costs;benefits;recency;information and ...
Kleijnen, J.P.C.
core +1 more source
STRATEGIST : a program that models strategy-driven and content-driven inference behavior [PDF]
, 1983 In the course of understanding a text, different readers use different inference strategies to guide their choice of interpretations of the events in the text.
Eiselt, Kurt P. +2 more
core +1 more source
Know Your Clients' behaviours: a cluster analysis of financial transactions
, 2020 In Canada, financial advisors and dealers are required by provincial securities commissions and self-regulatory organizations--charged with direct regulation over investment dealers and mutual fund dealers--to respectively collect and maintain Know Your ...
Feng, Longlong +3 more
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source