Results 241 to 250 of about 119,693 (290)

Electroacupuncture improves cyclophosphamide-induced bladder overactivity by reducing mechanotransduction in the rat urothelium. [PDF]

open access: yesJ Tradit Chin Med
Junwei HU   +7 more
europepmc   +1 more source
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The A1 adenosine receptor as a new player in microglia physiology

Glia, 2014
The purinergic system is highly involved in the regulation of microglial physiological processes. In addition to the accepted roles for the P2X4,7 and P2Y12 receptors activated by adenosine triphosphate (ATP) and adenosine diphosphate, respectively, recent evidence suggests a role for the adenosine A2A receptor in microglial cytoskeletal rearrangements.
L. Luongo   +15 more
semanticscholar   +5 more sources

The glycoprotein nature of A1 adenosine receptors [PDF]

open access: possibleBiochemical and Biophysical Research Communications, 1986
A1 adenosine receptors from different tissues and species were photoaffinity labelled and then the carbohydrate content was examined by both enzymatic and chemical treatment. Sodium dodecyl sulfate-polyacrylamide gel electrophoresis of the labelled membrane receptors shows that neuraminidase treatment alters the electrophoretic mobility of the receptor
Klotz, Karl-Norbert, Lohse, M. J.
openaire   +3 more sources

Allosteric modulators for the A1 adenosine receptor

Expert Opinion on Therapeutic Patents, 2004
The present invention provides compounds of formula (I) wherein R1, R2, R3, R4 and Q have a meaning as defined herein in the specification. The compounds of formula (I) are allosteric modulators of the A1 adenosine receptor and, thus, may be employed for the treatment of conditions mediated by the A1 adenosine receptor.
BARALDI, Pier Giovanni   +4 more
openaire   +5 more sources

Binding of an adenosine A1 receptor agonist and adenosine A1 receptor antagonist to sheep pineal membranes

European Journal of Pharmacology, 1997
The pineal organ of vertebrates produces melatonin and adenosine. In lower vertebrates, adenosine modulates melatonin production. We report herein that 2-chloro-cyclopentyl-[3H]-adenosine ([3H]CCPA: adenosine A1 receptor agonist) and [3H]-cyclopentyl-1,3-dipropylxanthine ([3H]DPCPX: adenosine A1 receptor antagonist), bind specifically to sheep pineal ...
Jack Falcón   +3 more
openaire   +4 more sources

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