Results 191 to 200 of about 93,761 (300)

Successful treatment of refractory chilblain lupus erythematosus with bosentan. [PDF]

Rheumatology (Oxford)
Gunawardana S, Clarke AJ, Lloyd-Lavery A, Dubey S.   +3 more
europepmc   +1 more source

Subcutaneous Treprostinil in PH Associated With Left Heart Disease or Chronic Lung Disease

Pulmonary Circulation, Volume 16, Issue 1, January 2026.
ABSTRACT Pulmonary hypertension (PH) associated with left heart disease (LHD‐PH) and pulmonary hypertension associated with chronic lung disease (CLD‐PH) are the most common PH subtypes but lack effective treatments. In a prospective cohort study, 90 patients (39 LHD‐PH, 51 CLD‐PH) with severe disease [pulmonary vascular resistance (PVR) > 5 Wood units
Roela Sadushi‐Koliçi, Leila Alajbegovic, Vladimir Gojic, Nika Skoro‐Sajer, Ioana Campean, Inbal Shafran, Deddo Mörtl, Christian Gerges, Irene M. Lang   +8 more
wiley   +1 more source

Signaling Molecules and Diagnosis of Cognitive Disorders: Current State and Prospects. [PDF]

Int J Mol Sci
Kvetnoy I, Kheyfets O, Safaniev L, Kheifets V, Mironova E, Kvetnaia T, Mazzoccoli G, Prashchayeu K, Gavrilova A.   +8 more
europepmc   +1 more source

Methamphetamine‐Associated Pulmonary Arterial Hypertension: Impact, Mechanisms, and a Framework for Management

Pulmonary Circulation, Volume 16, Issue 1, January 2026.
ABSTRACT Methamphetamine‐associated pulmonary arterial hypertension (Meth‐PAH) is an increasingly prevalent but understudied subtype of Group 1 pulmonary arterial hypertension (PAH). While most prevalent in the Western United States, its reach continues to expand with the evolving global methamphetamine epidemic.
Namita Sood, Jonika Weerasekare, Iryna Zhyvylo, Elena A. Goncharova, Teresa De Marco   +4 more
wiley   +1 more source

Cell-Specific Inducible Human <i>APOL1</i> Risk Variant Expression in Mice Causes Hypertension and Renal Damage. [PDF]

Circulation
Li F, Poudel B, Andrade-Silva M, Wu J, Raman A, Cruz-Morales E, Wahba J, Vassalotti A, Li C, Abedini A, Klötzer KA, Ding X, Hunter CA, Miner JJ, Susztak K.   +14 more
europepmc   +1 more source

Transmembrane Protein 100 Expression on Endothelial Cells Vascularizing Thrombi in Chronic Thromboembolic Pulmonary Hypertension Modulates TGFβ1−ALK1 Signaling During Angiogenesis

Pulmonary Circulation, Volume 16, Issue 1, January 2026.
ABSTRACT Endothelial cells within chronic pulmonary artery thrombi in CTEPH overexpress transmembrane protein 100 (TMEM100), an activin A receptor‐like kinase 1 (ACVRL1 or ALK1) signaling‐dependent gene, and TGFβ1 upregulated TMEM100 transcription in healthy lung ECs.
Magdalena L. Bochenek, Iman Ghasemi, Christoph B. Wiedenroth, Olympia Bikou, Ioannis Karampinis, Eric D. Roessner, Lukas Hobohm, Stefan Guth, Philipp Lurz, Stavros Konstantinides, Katrin Schäfer   +10 more
wiley   +1 more source

Endothelin-1 Stimulates the Growth of Visceral and Subcutaneous Human Preadipocytes through Similar and Alternative Signaling Pathways via Type A and Type B Endothelin Receptors: Potential Implications for Therapeutic Strategies for Obesity and Metabolic Disorders. [PDF]

Int J Med Sci
Siao AC, Kao YH, Kuo CC, Shyu HY, Kuo YC, Chiang WF, Wu KA, Shih LJ, Hsiao PJ.   +8 more
europepmc   +1 more source

Isolated Anti‐SS‐A Antibody Seropositivity as a Poor Prognostic Factor in Systemic Sclerosis: Insights From a Cohort of 307 Cases

The Journal of Dermatology, Volume 53, Issue 1, Page 41-53, January 2026.
ABSTRACT Systemic sclerosis is an autoimmune disease characterized by vasculopathy, fibrosis, and immune dysregulation. Anti‐SS‐A antibodies (anti‐SSA) have been reported to confer severe clinical manifestations in some Western and Japanese cohorts. We aimed to determine whether anti‐SSA seropositivity affects clinical outcomes in Japanese patients. We
Nana Ishida, Kazuki M. Matsuda, Hirohito Kotani, Hayakazu Sumida, Shinichi Sato   +4 more
wiley   +1 more source

Impact of thyroid hormones and serum endothelin levels on pediatric asthma control: a case-control study of an Indian population. [PDF]

Clin Exp Pediatr
Sathishbabu M, Ramasamy S, Ramachandran N, Palanisamy S, Subramaniam A.   +4 more
europepmc   +1 more source

Human hypoxia models in aerospace medicine: Potential applications for human pharmacological research

British Journal of Clinical Pharmacology, Volume 92, Issue 1, Page 58-72, January 2026.
Aerospace medicine required controlled terrestrial models to investigate influences of altered atmosphere conditions, such as hypoxia, on human health and performance. These models could potentially be expanded to encompass disease conditions or treatment targets regulated through hypoxia or hypercapnia.
Titiaan E. Post, Cayla Denney, Adam Cohen, Jens Jordan, Ulrich Limper   +4 more
wiley   +1 more source