Results 201 to 210 of about 93,761 (300)

Vasoactivity of Rac GTPase, Cytohesin and Kinase Inhibitors in Renal Interlobar and Coronary Arteries Reveals Shared and Distinct Patterns of Inhibitory Effects in Vascular and Prostate Smooth Muscle Contraction. [PDF]

Pharmacol Res Perspect
Liu G, Hu S, Tamalunas A, Kale O, Xu Y, Stief CG, Hennenberg M.   +6 more
europepmc   +1 more source

Addressing unmet needs for chronic kidney disease treatment in type 1 diabetes: A review

Diabetes, Obesity and Metabolism, Volume 28, Issue 1, Page 16-26, January 2026.
Abstract Chronic kidney disease (CKD) is a serious complication occurring in nearly one of three people with type 1 diabetes (T1D). Major therapeutic advances have been made in the management of CKD for people with type 2 diabetes (T2D), thereby improving their kidney, cardiovascular, and survival outcomes.
Katherine R. Tuttle, Linong Ji, Chantal Mathieu, Jonathan Rosen   +3 more
wiley   +1 more source

Mechanism of the analgesic effect of electroacupuncture on bone cancer pain through the neuro-immune system: progress based on animal experiments. [PDF]

Front Neurol
Qi P, Zhou M, Han W, Li H, Min L, Li J, Sun Z, Yin H.   +7 more
europepmc   +1 more source

Cardiovascular biomarkers and preeclampsia: A narrative review

European Journal of Clinical Investigation, Volume 56, Issue 1, January 2026.
Preeclampsia (PE) is a complex pregnancy disorder linked to cardiovascular disease (CVD) through shared risk factors and epidemiological associations. Cardiovascular biomarkers are valuable for predicting, diagnosing and assessing PE, as well as estimating future CVD risk. This review explores current cardiovascular biomarkers used in clinical practice
Johana Ullmo, Madalina Nicoleta Nan, Mónica Cruz‐Lemini, Carmen Garrido‐Gimenez, Judit Platero, Álvaro García‐Osuna, Pablo García‐Manau, Marcel Twickler, Elisa Llurba   +8 more
wiley   +1 more source

DNA methylation of the endothelin receptor B makes blue fish yellow. [PDF]

Nat Commun
Fang W, Blakkan D, Byrne A, Lee G, Bashier R, Fernald RD, Alvarado SG.   +6 more
europepmc   +1 more source

A matter arising: When should inflammatory and autoimmune rheumatic diseases be considered ‘early’?

European Journal of Clinical Investigation, Volume 56, Issue 1, January 2026.
Timely recognition of inflammatory and autoimmune rheumatic diseases (IARDs) is important to optimize the early diagnosis with tailored interventions and possible prevention of irreversible organ damage. This narrative review provides an update by summarizing the advances in identifying the early stages of rheumatoid arthritis, systemic sclerosis and ...
Elvis Hysa, Emanuele Gotelli, Carmen Pizzorni, Sabrina Paolino, Alberto Sulli, Vanessa Smith, Rosanna Campitiello, Maurizio Cutolo   +7 more
wiley   +1 more source

Vasoactive neuropeptide dysregulation: A novel mechanism of microvascular dysfunction in vascular cognitive impairment. [PDF]

Alzheimers Dement
Tambo W, Powell K, Wadolowski S, Unadkat P, Chang EH, LeDoux C, Sciubba D, Wang P, Huerta P, Li C.   +9 more
europepmc   +1 more source

Genomic Connectivity and Adaptation Signals of the Freshwater Sponge Ephydatia muelleri Across Its Distribution

Journal of Biogeography, Volume 53, Issue 1, January 2026.
ABSTRACT Aim Genetic connectivity and local adaptation were examined across the distribution of the freshwater sponge Ephydatia muelleri. Because it occupies an exceptional breadth of freshwater environments across a broad geographic range, this species offers key insights into biogeographic processes shaping genetic structure and adaptation in inland ...
Laura de la Cruz‐Castillejo, Robert Cassidy, Konstantina Mitsi, Carles Galià‐Camps, Ana Benítez‐López, Carlota Gracia‐Sancha, Jose Lorente‐Sorolla, Almudena Álvarez‐Fernández, Rocío Mozo, Stephen Kolomyjec, Scott Nichols, Renata Manconi, Raquel Pereira, Karen Evans, Valeria Itskovich, April L. Horton, Sally P. Leys, Sergi Taboada, Ana Riesgo   +18 more
wiley   +1 more source

The multifactorial role of HDAC9 at the maternal-fetal interface in the pathogenesis of preeclampsia. [PDF]

Clin Sci (Lond)
Opichka MA, McIntosh JJ, Grobe JL.
europepmc   +1 more source

Integrated Network Pharmacology, Single‐Cell Transcriptomics Unveil the Mechanistic Role of Morusin in Aortic Dissection

Journal of Cellular and Molecular Medicine, Volume 30, Issue 1, January 2026.
ABSTRACT Aortic dissection is a life‐threatening cardiovascular emergency with limited pharmacological options. This study focuses on elucidating the multi‐target and multi‐pathway mechanisms through which morusin mitigates aortic dissection progression, integrating network pharmacology, single‐cell transcriptomics and experimental validation.
Zhaomeng Wang, Haoran Zhang, Zhanxiong Xie, Yukun Xiang, Yiwen Fu, Zixun Wang, Haiqing Jiao, Nan Lin, Chenguang Niu, Chao Jiang, Lemin Zheng   +10 more
wiley   +1 more source