Results 161 to 170 of about 394,846 (264)

Role of oxidative/nitrosative stress in dysfunction of rat's intracerebral parenchymal arterioles in low sodium environment in the presence of vasopressin. [PDF]

Pflugers Arch
Aleksandrowicz M.
europepmc   +1 more source

Hyperhomocysteinemia‐Driven Ischemic Stroke: Unraveling Molecular Mechanisms and Therapeutic Horizons

Food Science &Nutrition, Volume 13, Issue 7, July 2025.
Neurotoxicity of Hcy. (A figure that best represents the scope of the paper.) Homocysteine can reduce the tightness of endothelial cell connections, increase vascular permeability, and damage the blood–brain barrier. Homocysteine activates various glutamate receptors on the surfaces of neurons and glial cells, triggering excitotoxicity, promoting the ...
Bin Li, Yushun Kou, Lingna Zhang, Lin Yi
wiley   +1 more source

Influence of Atherosclerosis-Associated Risk Factors on Expression of Endothelin Receptors in Advanced Atherosclerosis. [PDF]

Int J Mol Sci
Herbers O, Höltke C, Usai MV, Hochhalter J, Mallik M, Wildgruber M, Helfen A, Stölting M.   +7 more
europepmc   +1 more source

Endothelial Endothelin B Receptor-Mediated Prevention of Cerebrovascular Remodeling Is Attenuated in Diabetes Because of Up-Regulation of Smooth Muscle Endothelin Receptors

Journal of Pharmacology and Experimental Therapeutics, 2011
Aisha I. Kelly-Cobbs, Alex K. Harris, Mostafa M Elgebaly, Weiguo Li, Kamakshi Sachidanandam, V. Portik‐Dobos, Maribeth H. Johnson, A. Ergul   +7 more
semanticscholar   +1 more source

Lactate Metabolism and Lactylation Modification: New Opportunities and Challenges in Cardiovascular Disease

MedComm, Volume 6, Issue 7, July 2025.
Lactate, beyond a metabolic byproduct, regulates immunity and inflammation, linked to cardiovascular diseases (CVD) via metabolic reprogramming. Lactylation, a lactate‐driven epigenetic mark, modulates gene expression in fibrosis, lipid disorders, and CVD progression.
Mengyang Song, Bin Liu, Haiou Wang, Wei Sun   +3 more
wiley   +1 more source

AAV2-driven endothelin induces chronic reduced retinal blood flow/retinal ganglion cell loss in rats. [PDF]

Life Sci Alliance
Shi G, Sato K, Takahashi N, Ohno-Ohishi M, Murayama N, Yamaguchi C, Saigusa D, Nakazawa T.   +7 more
europepmc   +1 more source

Practical Considerations for Managing Patients on Tyvaso DPI (Treprostinil Inhalation Powder)

Pulmonary Circulation, Volume 15, Issue 3, July 2025.
ABSTRACT Pulmonary arterial hypertension (PAH) and pulmonary hypertension associated with interstitial lung disease (PH‐ILD) require a multifaceted, guideline‐directed management approach. This includes active patient participation in partnership with their healthcare team to minimize disease impact and improve survival.
Jennifer H. Keeley, Jacqueline Skarre, Lori Reed, Loida A. Johnson, Catherine Falardeau, Brittany N. J. Davis, Manisit Das, Howard Castillo, Susanne McDevitt   +8 more
wiley   +1 more source

Treating IgA Nephropathy: Looking at the Future Without Forgetting the Past. [PDF]

J Clin Med
Coppo R.
europepmc   +1 more source

Endothelin B receptor contribution to peripheral microvascular function in women with polycystic ovary syndrome

Journal of Physiology, 2011
M. Wenner, H. Taylor, N. Stachenfeld
semanticscholar   +1 more source

Towards the convergent therapeutic potential of G protein‐coupled receptors in autism spectrum disorders

British Journal of Pharmacology, Volume 182, Issue 14, Page 3044-3067, July 2025.
Abstract Autism spectrum disorders (ASDs) are diagnosed in 1/100 children worldwide, based on two core symptoms: deficits in social interaction and communication, and stereotyped behaviours. G protein‐coupled receptors (GPCRs) are the largest family of cell‐surface receptors that transduce extracellular signals to convergent intracellular signalling ...
Anil Annamneedi, Caroline Gora, Ana Dudas, Xavier Leray, Véronique Bozon, Pascale Crépieux, Lucie P. Pellissier   +6 more
wiley   +1 more source